Hacker News with Generative AI: Aging

'Healthy' Vitamin B12 Levels Not Enough to Ward Off Neuro Decline (ucsf.edu)
Meeting the minimum requirement for vitamin B12, needed to make DNA, red blood cells and nerve tissue, may not actually be enough – particularly if you are older. It may even put you at risk for cognitive impairment.
Lifestyle and environmental factors affect health and ageing more than our genes (ox.ac.uk)
A new study led by researchers from Oxford Population Health has shown that a range of environmental factors, including lifestyle (smoking and physical activity) and living conditions, have a greater impact on health and premature death than our genes.
Older AI models show signs of cognitive decline, study shows (livescience.com)
670nm red light exposure improved aged mitochondrial function, colour vision (nature.com)
Mitochondrial decline in ageing robs cells of ATP. However, animal studies show that long wavelength exposure (650–900 nm) over weeks partially restores ATP and improves function.
Facing the Music or Burying Our Heads in the Sand? (nlm.nih.gov)
Defenses that keep threatening information out of awareness are posited to reduce anxiety at the cost of longer-term dysfunction. By contrast, socioemotional selectivity theory suggests that preference for positively-valenced information is a late-life manifestation of adaptive emotion regulation.
Daily omega-3 fatty acids may help human organs stay young (medicalxpress.com)
Consuming one gram of omega-3 per day may slow down the rate of biological aging in humans, according to an analysis of data from a clinical trial involving over 700 older adults over a three-year period.
Muscle-Brain Crosstalk: How Skeletal Muscle Influences Neurocognitive Function (gethealthspan.com)
The term 'sarcopenia' might evoke images of weakening muscles and reduced physicality in the elderly. But this decline in muscle mass and strength, prevalent among older adults, has ramifications far beyond just physical fragility.
Omega-3s Can Slow Down Aging Process (news.uzh.ch)
A daily intake of one gram of omega-3s can slow down biological aging by up to four months, according to an analysis of clinical data from the international DO-HEALTH study led by the University of Zurich. For the first time, epigenetic clocks were used to measure the aging process.
An omega-3 dose a day could slow ageing process, 'healthspan' trial finds (theguardian.com)
A daily dose of omega-3 oils may slow the ageing process, according to a major clinical trial of interventions that aim to extend humans’ healthspan – the number of years spent in good health before a decline in old age.
Omega-3 supplements slow biological ageing (nature.com)
Omega-3 supplements have been shown to reduce the risk of falls and frailty in older people.
Emotional support across adulthood: A 60-year study of men’s social networks (psypost.org)
Emotional support networks among men shrink by 50% between the ages of 30 and 90, reflecting an average decrease from two to one emotional support providers, according to research published in Psychology & Aging.
How to Hit Peak Fitness After 40 (nytimes.com)
You can’t train in middle age like you did in your 20s. But if you’re strategic, your best days can still be ahead.
RNA molecule rejuvenates ageing mice by restoring old cells (nature.com)
Injecting old mice with an RNA molecule seems to reverse some signs of ageing — helping them to live longer, regrow hair and maintain their physical and mental abilities.
Japan's elderly are lonely and struggling. Some women choose to go to jail (cnn.com)
Drinking green tea linked to fewer white matter lesions in brains of olderAdults (medicalxpress.com)
Research led by the Kanazawa University Graduate School of Medical Sciences has reported a significant connection between higher green tea consumption and fewer cerebral white matter lesions in older adults without dementia.
Singapore is turning to AI to care for its rapidly aging population (restofworld.org)
By 2030, one in four people in Singapore will be over the age of 65. Authorities see potential in AI tools to assist in preventive illness care. An AI tool under development will use voice biomarkers to detect early signs of depression in seniors.
Two Waves of Aging: How Midlife Biomolecular Shifts Accelerate Decline (gethealthspan.com)
Aging has long been viewed as a gradual, linear decline, but recent findings suggest a far more dynamic process characterized by distinct biological transitions.
America Needs to Rethink What It Means to Be Old (theatlantic.com)
As 100-year lifespans become more common, the time has come for a new approach to school, work, and retirement.
Micro nutrients as immunomodulators in the ageing population (biomedcentral.com)
Immunosenescence, the slow degradation of immune function over time that is a hallmark and driver of aging, makes older people much more likely to be killed by common infections (such as flu) than young adults, but it also contributes greatly to rates of chronic inflammation in later life.
Is It Possible to Improve Memory or Are We Doomed to Forget as We Age? (2023) (nzherald.co.nz)
Memory is a fickle beast at the best of times, but it’s easy to think we’re sliding into a pandemic of forgetfulness, a collective midlife side-effect of living a life so fast-paced, we can’t possibly be expected to remember where we put the keys.
The Global Loss of the U-Shaped Curve of Happiness (afterbabel.com)
There is a literature of at least 600 published papers suggesting that happiness is U-shaped in age and, conversely, that unhappiness is hump-shaped in age.
What is ageing? Even the field's researchers can't agree (nature.com)
Researchers studying ageing disagree on just about everything — including what ageing is, whether it is a disease and when it starts — according to a survey of about 100 scientists working in the field.
Scientists explore longevity drugs for dogs that could also 'extend human life' (theguardian.com)
Researchers say drugs may be able to increase lifespan by extending health and thus shortening the rate of ageing
As drugstores close, older people are left in 'pharmacy deserts' (nytimes.com)
The risk of cancer fades past the age of 80 (sciencealert.com)
Aging brings two opposing trends in cancer risk: first, the risk climbs in our 60s and 70s, as decades of genetic mutations build up in our bodies. But then, past the age of around 80, the risk drops again – and a new study may explain a key reason why.
Why eating less slows ageing: this molecule is key (nature.com)
A naturally occurring compound involved in digestion lengthens lifespan in flies and makes old mice more youthful.
Revising our understanding of the aging process (rockefeller.edu)
A chart showing the explosive expansion in proportion of Granzyme K+ CD8+ T cells in mice across multiple organs as they age (Cao lab)
People are living longer – But spending more time in poor health (studyfinds.org)
ROCHESTER, Minn. — There’s no question that people are living longer today than centuries or even decades ago. However, in what might seem like a cruel irony, a new study finds people may not be living very well in those extra years.
Over 47? Have you gone through midlife transformation? (ycombinator.com)
The age of 47 is said to be the bottom of the midlife crisis U curve.
Do people reach 100 by surviving, delaying, or avoiding diseases? (springer.com)
Centenarians are perceived as pioneers of longevity, possessing the secrets to surpassing age 100. It remains unclear whether they achieve this by surviving, delaying, or avoiding diseases to a greater extent than their shorter-lived peers.