Hacker News with Generative AI: Aging

Premature Graying of Hair: Review with Updates (nlm.nih.gov)
Premature graying of hair (PGH) is defined as graying of hair before the age of 20 years in Caucasians and before 30 years in African American population.

Health, Hair Care, Genetics, Aging

118 points by luu 8 days ago | 108 comments

A new start after 60: I became a 'hummingbird' for people with dementia (theguardian.com)
At 63, Ann Thomas-Carter stepped into Framland care home for the first time and was immediately taken aback. “It wasn’t like a care home at all; it was this beautiful old manor house overlooking the Oxfordshire countryside and there were only 21 residents,” she says. “It felt like a big family, especially since everyone calls the residents ‘family members’. I fitted in right away.”

Dementia, Care Homes, Aging, Personal Stories, Human Interest

161 points by bookofjoe 8 days ago | 44 comments

Egg Consumption and 4-Year Change in Cognitive Function in Older Men and Women (mdpi.com)

Health, Nutrition, Aging, Cognitive Function, Research

7 points by gnabgib 18 days ago | 4 comments

Human Skin Rejuvenation via mRNA (biorxiv.org)
Aging is characterized by a gradual decline in function, partly due to accumulated molecular damage.

Biotechnology, Aging, mRNA, Genetics

25 points by birriel 19 days ago | 1 comments

Extension of the human lifespan, science fiction or reality? (peterattiamd.com)
Humanity may be reaching the limits of lifespan extension that are possible through treatment of chronic disease, but the door is still open for future advances in aging biology itself

Lifespan Extension, Science, Aging, Biology

5 points by nradov 23 days ago | 0 comments

What Developers Can Do to Continue to Program as They Age (infoq.com)
There’s a lot of pressure to stop programming as you get older, Gregory said. Many people move into management, or change careers entirely, or retire. She wants to still write code, and she wanted to explore what it is about getting older that can make it harder to remain a programmer:

Programming, Aging, Career Development, Technology

7 points by NomDePlum 25 days ago | 1 comments

Association between sleep duration trajectories and successful aging; study (biomedcentral.com)
Insufficient or excessive sleep duration are associated with increased risk of individual adverse outcomes. However, it remains largely unknown whether sleep duration trajectories are associated with overall health among older adults. This study aimed to examine the association between sleep duration trajectories and successful aging.

Health, Sleep, Aging, Research

5 points by gnabgib 25 days ago | 0 comments

Scientists can tweak one gene to extend lifespans by up to 30% (bgr.com)
Researchers have identified a particular cellular protein that affects aging. They’ve also managed to tweak this gene to produce it in fruit flies, extending their lives by up to 30 percent. The hope is that this discovery could further efforts to slow human aging and extend our lifespans.

Aging, Genetics, Longevity, Biology, Science

7 points by aard 27 days ago | 2 comments

Study reveals blood sugar control is a key factor in slowing brain aging (bgu.ac.il)
A new international study, led by Ben-Gurion University of the Negev as part of the DIRECT PLUS Brain MRI trial, has brought to light how blood sugar control can significantly impact brain health.

Health, Science, Brain Health, Diabetes, Aging

150 points by gnabgib 28 days ago | 148 comments

Insomnia, but not lack of sleep, may hasten brain shrinkage: study (ucsf.edu)
For adults in midlife, difficulty getting to sleep and waking up too early may accelerate brain atrophy that is associated with dementia.

Sleep Disorders, Dementia, Neuroscience, Aging

115 points by gnabgib 29 days ago | 65 comments

The Surprising Link Between VO₂ Max and Increased Brain Myelination (gethealthspan.com)
Physical exercise is increasingly recognized as a vital intervention for promoting brain health and mitigating cognitive decline associated with aging and neurodegenerative diseases such as Alzheimer's disease.

Health, Exercise, Brain Health, Aging

4 points by dtawfik1 37 days ago | 0 comments

Aging, Biomechanics, Health, Science

24 points by domofutu 40 days ago | 10 comments

Brain endurance training improves older adults' cognitive, physical performance (sciencedirect.com)
Cognitive and physical performance is impaired by aging and fatigue.

Cognitive Science, Aging, Health, Exercise

109 points by gnabgib 43 days ago | 33 comments

Transcript errors generate amyloid-like proteins in human cells (nature.com)
Aging is characterized by the accumulation of proteins that display amyloid-like behavior. However, the molecular mechanisms by which these proteins arise remain unclear. Here, we demonstrate that amyloid-like proteins are produced in a variety of human cell types, including stem cells, brain organoids and fully differentiated neurons by mistakes that occur in messenger RNA molecules.

Science, Biology, Aging, Proteins, Cellular Biology

4 points by bookofjoe 54 days ago | 0 comments

Brain rejuvenation breakthrough: Limiting glucose could spark new neuron growth (studyfinds.org)
STANFORD, Calif. — Could the secret to maintaining a youthful, sharp mind be as simple as watching our sugar intake? A new study from Stanford Medicine suggests that glucose plays a surprising role in the aging brain’s ability to produce new neurons.

Neuroscience, Aging, Health, Glucose, Brain

28 points by gnabgib 61 days ago | 16 comments

Study finds older adults who experience a fall are at increased risk of dementia (medicalxpress.com)
Researchers from Brigham and Women's Hospital, a founding member of the Mass General Brigham health care system, have published results showing that among older adults who sustained a traumatic injury, those who experienced falls were more likely to be subsequently diagnosed with Alzheimer's disease and related dementias.

Health, Aging, Dementia, Falls

5 points by amichail 63 days ago | 0 comments

The human heart shows signs of ageing after just a month in space (nature.com)
Over the course of just one month in space, engineered human heart tissue got weaker, its ‘beating’ patterns became irregular and it underwent molecular and genetic changes that mimicked the effect of ageing1.

Space Exploration, Human Biology, Aging, Health

19 points by belter 69 days ago | 6 comments

The human heart shows signs of ageing after just a month in space (nature.com)
Over the course of just one month in space, engineered human heart tissue got weaker, its ‘beating’ patterns became irregular and it underwent molecular and genetic changes that mimicked the effect of ageing1. The findings are published in the Proceedings of the National Academy of Sciences today.

Space, Health, Biology, Aging

125 points by gnabgib 71 days ago | 87 comments

Metformin decelerates aging clock in male monkeys (sciencedirect.com)
In a rigorous 40-month study, we evaluated the geroprotective effects of metformin on adult male cynomolgus monkeys, addressing a gap in primate aging research.

Aging, Medicine, Primate Research, Science

12 points by Metacelsus 76 days ago | 2 comments

Slowing the Pace of Brain Aging (erictopol.substack.com)
Using high-throughput plasma proteins in large cohorts with extended follow-up, 3 recent organ clock studies that I reviewed highlighted the marked inter-individual and inter-organ variability of the pace of brain aging, its association with mortality, and multiple potential modifiable factors.

Aging, Brain Health, Science, Biomarkers

16 points by EA-3167 81 days ago | 1 comments

Older Americans Are About to Lose a Lot of Weight (theatlantic.com)
People over 65 make up a sizable portion of Americans on GLP-1 drugs. That might be trouble.

Health, Aging, Pharmaceuticals, United States

17 points by paulpauper 81 days ago | 126 comments

Metformin decelerates aging clock in male monkeys (cell.com)
In a rigorous 40-month study, we evaluated the geroprotective effects of metformin on adult male cynomolgus monkeys, addressing a gap in primate aging research.

Aging, Health, Science, Medicine, Monkeys

205 points by tortilla 82 days ago | 209 comments

The Larger Brains of Humans Come with a Tragic Cost, Study Finds (sciencealert.com)
Intelligence has allowed our species to not just survive, but thrive across a range of environments. But new research reveals our advantageous smarts come at a cost: a much greater susceptibility to brain decay.

Human Evolution, Neuroscience, Science, Aging

24 points by wjSgoWPm5bWAhXB 86 days ago | 12 comments

Weight-loss jabs could 'slow down the clock' on biological ageing (thetimes.com)
Weight-loss jabs could ‘slow down the clock’ on biological ageing

Health, Aging, Medicine, Science, Weight Loss

15 points by bookofjoe 87 days ago | 2 comments

Rethinking Exercise: How Too Much Can Speed Up Aging, According to Finnish Study (2023) (thomashealthblog.com)

Exercise, Aging, Health, Finland, Studies

48 points by prmph 89 days ago | 51 comments

Feeling Suddenly Older? Scientists See Aging 'Waves' at 44 and 60 (wsj.com)

Aging, Biology, Science, Health

12 points by palidanx 90 days ago | 1 comments

The cost of senior care: Why aging farmers fear the nursing home (text.npr.org)