Hacker News with Generative AI: Aging

Drinking green tea linked to fewer white matter lesions in brains of olderAdults (medicalxpress.com)
Research led by the Kanazawa University Graduate School of Medical Sciences has reported a significant connection between higher green tea consumption and fewer cerebral white matter lesions in older adults without dementia.
Singapore is turning to AI to care for its rapidly aging population (restofworld.org)
By 2030, one in four people in Singapore will be over the age of 65. Authorities see potential in AI tools to assist in preventive illness care. An AI tool under development will use voice biomarkers to detect early signs of depression in seniors.
Two Waves of Aging: How Midlife Biomolecular Shifts Accelerate Decline (gethealthspan.com)
Aging has long been viewed as a gradual, linear decline, but recent findings suggest a far more dynamic process characterized by distinct biological transitions.
America Needs to Rethink What It Means to Be Old (theatlantic.com)
As 100-year lifespans become more common, the time has come for a new approach to school, work, and retirement.
Micro nutrients as immunomodulators in the ageing population (biomedcentral.com)
Immunosenescence, the slow degradation of immune function over time that is a hallmark and driver of aging, makes older people much more likely to be killed by common infections (such as flu) than young adults, but it also contributes greatly to rates of chronic inflammation in later life.
Is It Possible to Improve Memory or Are We Doomed to Forget as We Age? (2023) (nzherald.co.nz)
Memory is a fickle beast at the best of times, but it’s easy to think we’re sliding into a pandemic of forgetfulness, a collective midlife side-effect of living a life so fast-paced, we can’t possibly be expected to remember where we put the keys.
The Global Loss of the U-Shaped Curve of Happiness (afterbabel.com)
There is a literature of at least 600 published papers suggesting that happiness is U-shaped in age and, conversely, that unhappiness is hump-shaped in age.
What is ageing? Even the field's researchers can't agree (nature.com)
Researchers studying ageing disagree on just about everything — including what ageing is, whether it is a disease and when it starts — according to a survey of about 100 scientists working in the field.
Scientists explore longevity drugs for dogs that could also 'extend human life' (theguardian.com)
Researchers say drugs may be able to increase lifespan by extending health and thus shortening the rate of ageing
As drugstores close, older people are left in 'pharmacy deserts' (nytimes.com)
The risk of cancer fades past the age of 80 (sciencealert.com)
Aging brings two opposing trends in cancer risk: first, the risk climbs in our 60s and 70s, as decades of genetic mutations build up in our bodies. But then, past the age of around 80, the risk drops again – and a new study may explain a key reason why.
Why eating less slows ageing: this molecule is key (nature.com)
A naturally occurring compound involved in digestion lengthens lifespan in flies and makes old mice more youthful.
Revising our understanding of the aging process (rockefeller.edu)
A chart showing the explosive expansion in proportion of Granzyme K+ CD8+ T cells in mice across multiple organs as they age (Cao lab)
People are living longer – But spending more time in poor health (studyfinds.org)
ROCHESTER, Minn. — There’s no question that people are living longer today than centuries or even decades ago. However, in what might seem like a cruel irony, a new study finds people may not be living very well in those extra years.
Over 47? Have you gone through midlife transformation? (ycombinator.com)
The age of 47 is said to be the bottom of the midlife crisis U curve.
Do people reach 100 by surviving, delaying, or avoiding diseases? (springer.com)
Centenarians are perceived as pioneers of longevity, possessing the secrets to surpassing age 100. It remains unclear whether they achieve this by surviving, delaying, or avoiding diseases to a greater extent than their shorter-lived peers.
Cancer Risk Declines in Old Age, New Research Helps Explain Why (mskcc.org)
Premature Graying of Hair: Review with Updates (nlm.nih.gov)
Premature graying of hair (PGH) is defined as graying of hair before the age of 20 years in Caucasians and before 30 years in African American population.
A new start after 60: I became a 'hummingbird' for people with dementia (theguardian.com)
At 63, Ann Thomas-Carter stepped into Framland care home for the first time and was immediately taken aback. “It wasn’t like a care home at all; it was this beautiful old manor house overlooking the Oxfordshire countryside and there were only 21 residents,” she says. “It felt like a big family, especially since everyone calls the residents ‘family members’. I fitted in right away.”
Egg Consumption and 4-Year Change in Cognitive Function in Older Men and Women (mdpi.com)
Human Skin Rejuvenation via mRNA (biorxiv.org)
Aging is characterized by a gradual decline in function, partly due to accumulated molecular damage.
Extension of the human lifespan, science fiction or reality? (peterattiamd.com)
Humanity may be reaching the limits of lifespan extension that are possible through treatment of chronic disease, but the door is still open for future advances in aging biology itself
What Developers Can Do to Continue to Program as They Age (infoq.com)
There’s a lot of pressure to stop programming as you get older, Gregory said. Many people move into management, or change careers entirely, or retire. She wants to still write code, and she wanted to explore what it is about getting older that can make it harder to remain a programmer:
Association between sleep duration trajectories and successful aging; study (biomedcentral.com)
Insufficient or excessive sleep duration are associated with increased risk of individual adverse outcomes. However, it remains largely unknown whether sleep duration trajectories are associated with overall health among older adults. This study aimed to examine the association between sleep duration trajectories and successful aging.
Scientists can tweak one gene to extend lifespans by up to 30% (bgr.com)
Researchers have identified a particular cellular protein that affects aging. They’ve also managed to tweak this gene to produce it in fruit flies, extending their lives by up to 30 percent. The hope is that this discovery could further efforts to slow human aging and extend our lifespans.
Study reveals blood sugar control is a key factor in slowing brain aging (bgu.ac.il)
A new international study, led by Ben-Gurion University of the Negev as part of the DIRECT PLUS Brain MRI trial, has brought to light how blood sugar control can significantly impact brain health.
Insomnia, but not lack of sleep, may hasten brain shrinkage: study (ucsf.edu)
For adults in midlife, difficulty getting to sleep and waking up too early may accelerate brain atrophy that is associated with dementia.
The Surprising Link Between VO₂ Max and Increased Brain Myelination (gethealthspan.com)
Physical exercise is increasingly recognized as a vital intervention for promoting brain health and mitigating cognitive decline associated with aging and neurodegenerative diseases such as Alzheimer's disease.
Age-related changes in gait, balance, and strength parameters (plos.org)
Brain endurance training improves older adults' cognitive, physical performance (sciencedirect.com)
Cognitive and physical performance is impaired by aging and fatigue.