Hacker News with Generative AI: Metabolism

Oligodendroglial fatty acid metabolism as a CNS energy reserve (nature.com)
Brain function requires a constant supply of glucose. However, the brain has no known energy stores, except for glycogen granules in astrocytes. In the present study, we report that continuous oligodendroglial lipid metabolism provides an energy reserve in white matter tracts.
Modeling sex-specific whole-body metabolic responses to feeding and fasting (sciencedirect.com)
Men generally favor carbohydrate metabolism, while women lean towards lipid metabolism, resulting in significant sex-based differences in energy oxidation across various metabolic states such as fasting and feeding.
Adipocyte deletion of an oxygen-sensor sustains elevated energy expenditure (nature.com)
Metabolism and diet linked to root of bipolar depression (theguardian.com)
Illness could be treated as a physical, rather than mood, disorder, according to scientists in Edinburgh
Obesity is driven by a build-up of molecular mesh around hunger neurons (nature.com)
The accumulation of a network of proteins and sugars called the extracellular matrix stops insulin from reaching hunger-regulating neurons, disrupting normal food intake and metabolism, and contributing to obesity.
Metabolism – How to reduce half-life of caffeine? (stackexchange.com)
Caffeine has a typical half-life of 5–6 hours, but some of us take much longer to metabolize it (1 cup of coffee at breakfast can leave me sleepless that night).
GLP-1 therapy increases visceral adipose tissue metabolic activity (wiley.com)
Diet impacts metabolic disease via gut microbiota alterations (sciencedirect.com)
Kombucha-associated microbes alter host metabolism & suppress lipid accumulation (plos.org)
Metabolism of autism reveals developmental origins (medicalxpress.com)
Exercise, metabolism, and weight: New research from The Biggest Loser (2022) (health.harvard.edu)
It's not your age that's slowing your metabolism, new research says (2021) (cnn.com)