Hacker News with Generative AI: Metabolism

Metabolism Can Shape Cells' Destinies (quantamagazine.org)
A growing body of work suggests that cell metabolism — the chemical reactions that provide energy and building materials — plays a vital, overlooked role in the first steps of life.

Biology, Cellular Biology, Metabolism

51 points by isaacfrond 13 days ago | 1 comments

The Role of Brown Fat and Circadian Rhythms (gethealthspan.com)
Circadian rhythms regulate numerous physiological processes, including metabolism, and their disruption is increasingly linked to obesity, insulin resistance, and metabolic disorders. Concurrently, brown adipose tissue (BAT) has emerged as a key player in metabolic health, capable of burning calories through thermogenesis and significantly influencing glucose and lipid metabolism. Recent evidence indicates that BAT activity is strongly influenced by circadian timing, exhibiting diurnal fluctuations that peak in the morning.

Circadian Rhythms, Metabolism, Brown Fat, Obesity, Health

6 points by dtawfik1 17 days ago | 0 comments

Gut microbiota functions:metabolism of nutrients and other food components(2017) (nlm.nih.gov)
The diverse microbial community that inhabits the human gut has an extensive metabolic repertoire that is distinct from, but complements the activity of mammalian enzymes in the liver and gut mucosa and includes functions essential for host digestion.

Microbiology, Human Health, Nutrition, Metabolism

6 points by BiraIgnacio 50 days ago | 1 comments

Study finds unexpected benefit to plant-based diet (independent.co.uk)
Swapping out meat and dairy can do more than just help animals and the planet, according to a new study that shows a vegan diet can transform your gut and metabolism.

Health, Nutrition, Veganism, Gut Health, Metabolism

4 points by hochmartinez 86 days ago | 0 comments

Oligodendroglial fatty acid metabolism as a CNS energy reserve (nature.com)
Brain function requires a constant supply of glucose. However, the brain has no known energy stores, except for glycogen granules in astrocytes. In the present study, we report that continuous oligodendroglial lipid metabolism provides an energy reserve in white matter tracts.

Neuroscience, Brain, Metabolism, Energy, Biology

4 points by PaulHoule 168 days ago | 0 comments

Modeling sex-specific whole-body metabolic responses to feeding and fasting (sciencedirect.com)
Men generally favor carbohydrate metabolism, while women lean towards lipid metabolism, resulting in significant sex-based differences in energy oxidation across various metabolic states such as fasting and feeding.

Science, Biology, Metabolism, Gender Differences, Nutrition

4 points by gnabgib 177 days ago | 0 comments

Adipocyte deletion of an oxygen-sensor sustains elevated energy expenditure (nature.com)

Science, Biology, Genetics, Metabolism

7 points by PaulHoule 186 days ago | 0 comments

Metabolism and diet linked to root of bipolar depression (theguardian.com)
Illness could be treated as a physical, rather than mood, disorder, according to scientists in Edinburgh

Mental Health, Bipolar Disorder, Science, Diet, Metabolism

8 points by rippeltippel 195 days ago | 2 comments

Obesity is driven by a build-up of molecular mesh around hunger neurons (nature.com)
The accumulation of a network of proteins and sugars called the extracellular matrix stops insulin from reaching hunger-regulating neurons, disrupting normal food intake and metabolism, and contributing to obesity.

Obesity, Neuroscience, Biology, Metabolism, Cellular Biology

3 points by bookofjoe 197 days ago | 1 comments

Metabolism – How to reduce half-life of caffeine? (stackexchange.com)
Caffeine has a typical half-life of 5–6 hours, but some of us take much longer to metabolize it (1 cup of coffee at breakfast can leave me sleepless that night).

Caffeine, Health, Metabolism, Biology

10 points by bilsbie 199 days ago | 0 comments

GLP-1 therapy increases visceral adipose tissue metabolic activity (wiley.com)

GLP-1 therapy, Metabolism, Health, Obesity, Visceral Fat

105 points by gumby 224 days ago | 118 comments

Diet impacts metabolic disease via gut microbiota alterations (sciencedirect.com)

Diet, Health, Gut Microbiota, Metabolism, Disease

19 points by mlsys_djw 247 days ago | 4 comments

Kombucha-associated microbes alter host metabolism & suppress lipid accumulation (plos.org)

Kombucha, Microbes, Metabolism, Health, Science

29 points by bookofjoe 314 days ago | 23 comments

Metabolism of autism reveals developmental origins (medicalxpress.com)