Hacker News with Generative AI: Genetics

AI-designed DNA controls genes in healthy mammalian cells for first time (crg.eu)
A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

Generative AI, Biology, Science, Genetics

3 points by geox 18 hours ago | 0 comments

Parts of our DNA may mutate far faster than previously thought (medicalxpress.com)
Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been off-limits to researchers—until now.

Genetics, DNA, Science, Health, Research

6 points by PaulHoule 1 day ago | 0 comments

Don't need much sleep? Mutation linked to thriving with little rest (nature.com)
Some people can function well on little sleep.Credit: Oleg Breslavtsev/Getty

Genetics, Sleep, Health, Science

11 points by lentoutcry 3 days ago | 1 comments

A structured coalescent model reveals deep ancestral structure shared by humans (nature.com)
Understanding the history of admixture events and population size changes leading to modern humans is central to human evolutionary genetics.

Genetics, Ancestry, Human Evolution, Population Genetics

6 points by georgecmu 4 days ago | 0 comments

Ancient DNA from the green Sahara reveals ancestral North African lineage (nature.com)
Although it is one of the most arid regions today, the Sahara Desert was a green savannah during the African Humid Period (AHP) between 14,500 and 5,000 years before present, with water bodies promoting human occupation and the spread of pastoralism in the middle Holocene epoch1.

Ancient History, Genetics, Africa, Climate Change, Archaeology

52 points by gnabgib 5 days ago | 6 comments

Ancient DNA unearths a new race from a verdant North African interlude (razibkhan.com)
These 7000-year-old humans are neither Eurasian nor sub-Saharan African

Genetics, Archaeology, Africa

12 points by pseudolus 5 days ago | 0 comments

Genetic links with bipolar disorder identified (europesays.com)
In the largest genome-wide study of bipolar disorder to date, an international team involving UCL researchers has identified 298 regions of the genome containing DNA variations that increase risk for the disorder.

Genetics, Bipolar Disorder, Science, Research

17 points by lentoutcry 5 days ago | 0 comments

Blocking surprising master regulator of immunity eradicates liver tumors in mice (med.stanford.edu)
A protein identified nearly 40 years ago for its ability to stimulate the production of red blood cells plays a surprising, critical role in dampening the immune system’s response to cancer.

Cancer Research, Immunology, Medicine, Genetics

18 points by rbanffy 7 days ago | 2 comments

Ancient DNA Unveils the Cosmopolitan Heart of the Phoenician-Punic Civilization (allthathistory.com)
Imagine a bustling port in ancient Carthage, circa 600 BCE, where Phoenician sailors unload fragrant cedarwood from Lebanon, North African potters shape intricate ostrich-egg urns, and Sicilian merchants barter for shimmering Aegean textiles. This was the Punic world—a dazzling crossroads of cultures, united not by conquest but by the restless tides of trade and human connection.

Ancient History, Archaeology, Mediterranean History, Phoenicians, Genetics

25 points by speckx 8 days ago | 3 comments

Origins of common lung cancer that affects smokers discovered (medicalxpress.com)
The "cell of origin" of the second most common lung cancer and the way that it becomes dominant in the lung have been discovered in a new study in mice and humans by researchers at UCL, the Wellcome Sanger Institute and the University of Cambridge.

Lung Cancer, Science, Medical Research, Genetics

12 points by mdp2021 8 days ago | 0 comments

New study reveals how cleft lip and cleft palate can arise (news.mit.edu)
MIT biologists have discovered how a genetic variant often found in people with these facial malformations leads to the development of cleft lip and cleft palate.

Genetics, Health, Science, Facial Malformations

3 points by gmays 8 days ago | 0 comments

All roses were once yellow (phys.org)
Red roses, the symbol of love, were likely yellow in the past, indicates a large genomic analysis by researchers from Beijing Forestry University, China.

Genetics, Botany, Evolution, China, Research

48 points by gmays 8 days ago | 6 comments

Metagenomics test saves woman's sight after mystery infection (bbc.co.uk)
A 29-year-old doctor from Bristol has had her eyesight saved after a "game-changing" test identified a mystery infection that had plagued her health for five years.

Medicine, Genetics, Science, Health

204 points by neversaydie 9 days ago | 80 comments

AI helps unravel a cause of Alzheimer’s and identify a therapeutic candidate (today.ucsd.edu)
A new study found that a gene recently recognized as a biomarker for Alzheimer’s disease is actually a cause of it, due to its previously unknown secondary function.

Alzheimer's Disease, Genetics, AI, Therapeutics

319 points by pedalpete 11 days ago | 160 comments

Eugenics is on the rise again: human geneticists must take a stand (nature.com)
In 1924, motivated by the rising eugenics movement, the United States passed the Johnson–Reed Act, which limited immigration to stem “a stream of alien blood, with all its inherited misconceptions”.

Eugenics, Genetics, History, Science, Ethics

14 points by geox 12 days ago | 1 comments

Century-old genetics mystery of Mendel's peas solved (nature.com)
Researchers pinpoint the genes responsible for the final three pea traits studied by the famed citizen scientist.

Genetics, Science, Biology, History

21 points by Brajeshwar 14 days ago | 14 comments

The Australians hardwired to be up through the night (abc.net.au)
Abhinav Shrivastava is a rare natural night owl.

Sleep, Biology, Australia, Genetics

8 points by meander_water 14 days ago | 0 comments

The complex origin story of domestic cats (phys.org)
Researchers looking into the origin of domestic cats have long considered that cats likely accompanied early farmers during the Neolithic, spreading through Europe alongside the adoption of agriculture.

Cats, Genetics, History, Agriculture, Europe

139 points by gmays 17 days ago | 86 comments

23andMe won permission from a judge to sell customers' medical and ancestry data (fortune.com)
23andMe says it won permission from a judge to sell customers’ medical and ancestry data.

Privacy, Genetics, Healthcare, Business

5 points by timojaask 18 days ago | 3 comments

Red, pink or white, all roses were once yellow says genomic analysis (phys.org)
Red roses, the symbol of love, were likely yellow in the past, indicates a large genomic analysis by researchers from Beijing Forestry University, China.

Genetics, Botany, Research, Science, Color

6 points by pseudolus 18 days ago | 0 comments

Certain sunflower strains can be induced to form seeds without pollination (phys.org)
Syngenta Biotechnology China-led research, with partners in the U.S., France, the UK, Chile, the Netherlands, Argentina, and across China, has discovered that sunflowers can form viable haploid seeds through parthenogenesis in the absence of pollination.

Agriculture, Genetics, Science, Biology

5 points by PaulHoule 20 days ago | 0 comments

Congress Is Investigating 23andMe's Handling of Personal Data (gizmodo.com)
Republican lawmakers associated with the House Committee on Energy and Commerce are probing the 23andMe bankruptcy out of concern for Americans’ DNA information.

Genetics, Privacy, Politics, Regulation

6 points by rntn 20 days ago | 1 comments

The complex origin story of domestic cats: Research points to Tunisia (phys.org)
Researchers looking into the origin of domestic cats have long considered that cats likely accompanied early farmers during the Neolithic, spreading through Europe alongside the adoption of agriculture.

Genetics, History, Animals, Science, Tunisia

14 points by pseudolus 22 days ago | 0 comments

The unusual genetic inheritance that could change Alzheimer's treatment (nature.com)
The genes of a Colombian woman who beat the odds might lead to a new way to tackle the disease.

Genetics, Alzheimer's, Medical Research, Colombia

4 points by sohkamyung 22 days ago | 0 comments

The Genetic Puzzle of Autism: Why Some Develop It and Others Don't (bbc.com)
Genetic factors are thought to play a major role in the development of autism – but for decades what they are has proven elusive. Now scientists are starting to uncover clues.

Genetics, Autism, Science, Health

7 points by Korling 23 days ago | 0 comments

Our DNA Is at Risk of Hacking – Warn Scientistswise (newswise.com)
Publicly accessible DNA research is a prime target for hackersRisks threaten individual privacy, scientific integrity, and national securityGovernment and other agencies need to prioritise investment in cyber-biosecurity research

Cybersecurity, Genetics, Privacy, Science

6 points by smb111 23 days ago | 0 comments

Why educational inequality runs in families: Genetics more than environment (osf.io)

Education, Genetics, Social Inequality

24 points by mpweiher 26 days ago | 3 comments

7k-year-old skeletons from the green Sahara reveal a mysterious human lineage (smithsonianmag.com)
Researchers recently sequenced the genomes of two naturally mummified women found in Libya

Ancient History, Genetics, Archaeology, Africa

96 points by pseudolus 27 days ago | 33 comments

One of the Most Egregious Ripoffs in the History of Science – The Race to DNA (nautil.us)
A new history of the race to decipher DNA reveals Shakespearean plots of scheming.

Science, History, DNA, Genetics, Biotechnology

38 points by robaato 28 days ago | 11 comments

Mammoth genetic diversity throughout the last million years (sciencedaily.com)
A new genomic study has uncovered long-lost genetic diversity in mammoth lineages spanning over a million years, providing new insights into the evolutionary history of these animals.

Genetics, Paleontology, Evolution, Genomics, Animals

23 points by docmechanic 29 days ago | 2 comments