Hacker News with Generative AI: Genetics

The Ancient Horsemen Who Created the Modern World (wsj.com)
For about half the people alive today, the story of where they came from just became clearer.
Ancient human DNA recovered from a Palaeolithic pendant (nature.com)
Artefacts made from stones, bones and teeth are fundamental to our understanding of human subsistence strategies, behaviour and culture in the Pleistocene.
Woman's DNA discovered in 20k year old deer-tooth pendant (2023) (cbc.ca)
Scientists have discovered a woman's DNA preserved in a 20,000 year old deer-tooth pendant.
Humans Have a Third Set of Teeth. New Medicine May Help Them Grow. (popularmechanics.com)
A study out of Japan showed how targeting genes can regrow teeth in animals. Now, the team has turned to a human clinical trial. By targeting the USAG-1 gene, researchers believe that they can help people without a full set of teeth regrow teeth. The team says that humans have a third set of teeth available as buds, ready to grow as needed.
"Wooly mice" a test run for mammoth gene editing (arstechnica.com)
On Tuesday, the team behind the plan to bring mammoth-like animals back to the tundra announced the creation of what it is calling wooly mice, which have long fur reminiscent of the woolly mammoth.
Men with higher-quality sperm live longer, study finds (theguardian.com)
Sperm may be the canaries in the coalmine for male health, according to research that reveals men with higher-quality semen live longer.
"Wooly mice" a test run for mammoth gene editing (arstechnica.com)
On Tuesday, the team behind the plan to bring mammoth-like animals back to the tundra announced the creation of what it is calling wooly mice, which have long fur reminiscent of the woolly mammoth.
Woolly mice designed to engineer mammoth-like elephants (bbc.co.uk)
Genetically engineered woolly mice could one day help populate the Arctic with hairy, genetically modified elephants and help stop the planet warming.
Scientists aiming to bring back woolly mammoth create woolly mice (theguardian.com)
A plan to revive the mammoth is on track, scientists have said after creating a new species: the woolly mouse.
The 'bionic' girl from the UK who feels no pain or hunger (2023) (firstpost.com)
A UK teenager named Olivia Farnsworth has a rare chromosome condition known as chromosome 6 deletion, which does not make her feel hungry, pain or sense of danger. It is believed she is the only person in the world who possesses all three symptoms together
Ancient DNA Points to Origins of Indo-European Language (nytimes.com)
A new study claims to have identified the first speakers of Indo-European language, which gave rise to English, Sanskrit and hundreds of others.
Chimeric particles expand species boundaries in chromosomal island mobilization (biorxiv.org)
Some mobile genetic elements spread among unrelated bacterial species through unknown mechanisms.
Sneaky bamboo can control the genes of the Pandas eating it, scientists discover (livescience.com)
Violence alters human genes for generations, researchers discover (news.ufl.edu)
In 1982, the Syrian government besieged the city of Hama, killing tens of thousands of its own citizens in sectarian violence. Four decades later, rebels used the memory of the massacre to help inspire the toppling of the Assad family that had overseen the operation.
Explaining an apparent 17:1 female to male population question during the Neoli (sciencealert.com)
Around 7,000 years ago - all the way back in the Neolithic - something really peculiar happened to human genetic diversity. Over the next 2,000 years, and seen across Africa, Europe and Asia, the genetic diversity of the Y chromosome collapsed, becoming as though there was only one man for every 17 women.
Mapping the yerba mate genome reveals the evolution of caffeine biosynthesis (phys.org)
Mapping the yerba mate genome reveals surprising facts about the evolution of caffeine
New reviews for Lumina Probiotic, the genetically engineered toothpaste (sfstandard.com)
In January of last year, a handful of tech elites flew to Honduras to try a single-use toothpaste that wasn’t available in the U.S. Shelling out up to $20,000 for a dose, they hoped the genetically engineered dental rinse might permanently ward off cavities.
Biologists discover a new type of control over RNA splicing (phys.org)
MIT biologists have now discovered a new layer of regulation that helps to determine which sites on the messenger RNA molecule the spliceosome will target.
Lifestyle and environmental factors affect health and ageing more than our genes (ox.ac.uk)
A new study led by researchers from Oxford Population Health has shown that a range of environmental factors, including lifestyle (smoking and physical activity) and living conditions, have a greater impact on health and premature death than our genes.
Show HN: Synergetica – A Modern, End-to-End Genetic Circuit Design Desktop App (github.com/khokao)
Engineering of human cells reveals genome's resilience to structural changes (phys.org)
The most complex engineering of human cell lines ever has been achieved by scientists, revealing that our genomes are more resilient to significant structural changes than was previously thought.
A former Navy mechanic defied genetic odds of inherited Alzheimer's disease (medicalxpress.com)
Researchers at Washington University School of Medicine in St. Louis have conducted a longitudinal study on an individual carrying the presenilin 2 (PSEN2) p.Asn141Ile mutation, a genetic variant known to cause dominantly inherited Alzheimer's disease (DIAD).
Several Psychiatric Disorders Share the Same Root Cause (sciencealert.com)
Researchers recently discovered that eight different psychiatric conditions share a common genetic basis.
Bird flu variant found in Nevada cows shows signs of adaptation to mammals (cnn.com)
Ancient-DNA study identifies originators of Indo-European language family (hms.harvard.edu)
A pair of landmark studies has genetically identified the originators of the massive Indo-European family of 400-plus languages.
Dyson Tree (wikipedia.org)
A Dyson tree is a hypothetical genetically engineered plant (perhaps resembling a tree) capable of growing inside a comet, suggested by the physicist Freeman Dyson.
The genetic key to bipolar disorder (med.uio.no)
In the largest study conducted to date on the genetics of bipolar disorder, researchers have identified 36 genes linked to the condition.
Neanderthals' blood type may help explain their demise, new study finds (livescience.com)
Ancient genomes reveal an Iron Age society centred on women (tcd.ie)
An international team of geneticists, led by those from Trinity, has joined forces with archaeologists from Bournemouth University to decipher the structure of British Iron Age society, finding evidence of female political and social empowerment.
Sex Begins in the Womb (2001) (nlm.nih.gov)
Sex differences occur throughout the life span, although their specific expression varies at different at stages of life.