Hacker News with Generative AI: Genetics

Nanoparticle-cell link enables EM wireless programming of transgene expression (phys.org)
Recent technological advances are fueling the development of cutting-edge technologies that can monitor and control physiological processes with high precision.

Nanotechnology, Biology, Wireless Technology, Genetics

31 points by bookofjoe 12 days ago | 3 comments

Mother's Curse (wikipedia.org)
In biology, mother's curse is an evolutionary effect that males inherit deleterious mitochondrial genome (mtDNA) mutations from their mother, while those mutations are beneficial, neutral or less deleterious to females.

Biology, Genetics, Evolution, Mitochondrial DNA

6 points by teleforce 14 days ago | 0 comments

Rice inherits tolerance to cold without DNA changes (nature.com)
Rice plants can inherit tolerance to cold without changes to their genomes, according to a decade-long study1 carried out by researchers in China.

Genetics, Agriculture, Science, Rice

9 points by GolfPopper 15 days ago | 1 comments

Scientists find 16 new Alzheimer's-linked genes using multi-ancestry genome data (psypost.org)
A new study published in Alzheimer’s & Dementia has identified 16 novel genetic regions associated with Alzheimer’s disease by analyzing whole genome sequencing data from a large, ethnically diverse group of individuals.

Alzheimer's Disease, Genetics, Research, Science, Health

6 points by lentoutcry 15 days ago | 0 comments

Largest-ever ancient DNA study on a medieval cemetery reveals genetic history (kuleuven.be)
Geneticists from KU Leuven and international colleagues have conducted the largest ancient DNA study ever performed on human remains from a single medieval burial site.

Genetics, Archaeology, History, Medieval Period, DNA

4 points by isaacfrond 15 days ago | 0 comments

Newfound Mechanism Rewires Cellular Energy Processing for Drastic Weight Loss (nyulangone.org)
Mice genetically engineered to lack the ability to make the amino acid cysteine, and fed a cysteine-free diet, lost 30 percent of their body weight in just one week, a new study shows.

Genetics, Weight Loss, Metabolic Research, Cellular Biology

16 points by gnabgib 16 days ago | 5 comments

23andMe Sells Gene-Testing Business to DNA Drug Maker Regeneron (bloomberg.com)
Bankrupt genetic-testing firm 23andMe agreed to sell its data bank, which once contained DNA samples from about 15 million people, to the drug developer Regeneron Pharmaceuticals for $256 million.

Genetics, Healthcare, Business, Acquisitions

221 points by wslh 19 days ago | 127 comments

Williams Syndrome: The people who are too friendly (bbc.com)
People with Williams Syndrome treat strangers as their new best friends. Now the condition is giving clues to our evolutionary past – and what makes us human.

Genetics, Psychology, Social Behavior, Evolution

17 points by bookofjoe 21 days ago | 1 comments

Williams Syndrome: The people who are too friendly (bbc.com)
People with Williams Syndrome treat strangers as their new best friends. Now the condition is giving clues to our evolutionary past – and what makes us human.

Genetics, Psychology, Social Behavior, Human Evolution

10 points by neom 22 days ago | 0 comments

Decades-long mystery of ginger cats revealed (bbc.com)

Cats, Science, Genetics, Biology

14 points by colinprince 22 days ago | 0 comments

US doctors rewrite DNA of infant with genetic disorder in medical first (theguardian.com)
Doctors in the US have become the first to treat a baby with a customised gene-editing therapy after diagnosing the child with a severe genetic disorder that kills about half of those affected in early infancy.

Genetics, Medical Technology, Science, Healthcare

9 points by pseudolus 22 days ago | 0 comments

Mice grow bigger brains when given this stretch of human DNA (nature.com)
Researchers have identified a genetic dial in the human brain that, when inserted in mice, boosts their brain size by about 6.5%.

Genetics, Neuroscience, Research, Animal Studies

62 points by pavel_lishin 24 days ago | 44 comments

New study sheds light on health differences between sexes (medicalxpress.com)
The results of an international study led by researchers from Queen Mary University of London's Precision Healthcare University Research Institute (PHURI) shed new light on the underlying biological mechanisms which cause differences in health risks, symptoms and outcomes between males and females.

Health, Sex Differences, Biology, Research, Genetics

6 points by pseudolus 25 days ago | 0 comments

Olivia Farnsworth. The "Bionic Teen" Who Feels No Pain (medium.com)
Imagine walking away from a car accident without a scratch, while everyone around you is screaming in horror. That’s Olivia Farnsworth’s reality. Dubbed the “Bionic Teen,” this young girl from the UK doesn’t feel pain, hunger, or fatigue due to a rare genetic condition known as chromosome 6 deletion. Her story is not just mind-blowing; it’s a reminder of how little we truly understand about the human body.

Genetics, Medicine, Rare Conditions, Human Body, Science

4 points by thunderbong 27 days ago | 2 comments

AI-designed DNA controls genes in healthy mammalian cells for first time (crg.eu)
A study published today in the journal Cell marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.

Generative AI, Biology, Science, Genetics

4 points by geox 30 days ago | 0 comments

DNA is maybe 60-750MB of data (dynomight.net)
This is an article that just appeared in Asimov Press, who kindly agreed that I could publish it here and also humored my deep emotional need to use words like “Sparklepuff”.

Genetics, Data Storage, Science

57 points by MattSayar 30 days ago | 31 comments

Parts of our DNA may mutate far faster than previously thought (medicalxpress.com)
Knowing how human DNA changes over generations is essential to estimating genetic disease risks and understanding how we evolved. But some of the most changeable regions of our DNA have been off-limits to researchers—until now.

Genetics, DNA, Science, Health, Research

6 points by PaulHoule 30 days ago | 0 comments

Don't need much sleep? Mutation linked to thriving with little rest (nature.com)
Some people can function well on little sleep.Credit: Oleg Breslavtsev/Getty

Genetics, Sleep, Health, Science

11 points by lentoutcry 32 days ago | 1 comments

A structured coalescent model reveals deep ancestral structure shared by humans (nature.com)
Understanding the history of admixture events and population size changes leading to modern humans is central to human evolutionary genetics.

Genetics, Ancestry, Human Evolution, Population Genetics

6 points by georgecmu 33 days ago | 0 comments

Ancient DNA from the green Sahara reveals ancestral North African lineage (nature.com)
Although it is one of the most arid regions today, the Sahara Desert was a green savannah during the African Humid Period (AHP) between 14,500 and 5,000 years before present, with water bodies promoting human occupation and the spread of pastoralism in the middle Holocene epoch1.

Ancient History, Genetics, Africa, Climate Change, Archaeology

53 points by gnabgib 33 days ago | 6 comments

Ancient DNA unearths a new race from a verdant North African interlude (razibkhan.com)
These 7000-year-old humans are neither Eurasian nor sub-Saharan African

Genetics, Archaeology, Africa

12 points by pseudolus 33 days ago | 0 comments

Genetic links with bipolar disorder identified (europesays.com)
In the largest genome-wide study of bipolar disorder to date, an international team involving UCL researchers has identified 298 regions of the genome containing DNA variations that increase risk for the disorder.

Genetics, Bipolar Disorder, Science, Research

17 points by lentoutcry 34 days ago | 0 comments

Blocking surprising master regulator of immunity eradicates liver tumors in mice (med.stanford.edu)
A protein identified nearly 40 years ago for its ability to stimulate the production of red blood cells plays a surprising, critical role in dampening the immune system’s response to cancer.

Cancer Research, Immunology, Medicine, Genetics

18 points by rbanffy 36 days ago | 2 comments

Ancient DNA Unveils the Cosmopolitan Heart of the Phoenician-Punic Civilization (allthathistory.com)
Imagine a bustling port in ancient Carthage, circa 600 BCE, where Phoenician sailors unload fragrant cedarwood from Lebanon, North African potters shape intricate ostrich-egg urns, and Sicilian merchants barter for shimmering Aegean textiles. This was the Punic world—a dazzling crossroads of cultures, united not by conquest but by the restless tides of trade and human connection.

Ancient History, Archaeology, Mediterranean History, Phoenicians, Genetics

25 points by speckx 36 days ago | 3 comments

Origins of common lung cancer that affects smokers discovered (medicalxpress.com)
The "cell of origin" of the second most common lung cancer and the way that it becomes dominant in the lung have been discovered in a new study in mice and humans by researchers at UCL, the Wellcome Sanger Institute and the University of Cambridge.

Lung Cancer, Science, Medical Research, Genetics

12 points by mdp2021 36 days ago | 0 comments

New study reveals how cleft lip and cleft palate can arise (news.mit.edu)
MIT biologists have discovered how a genetic variant often found in people with these facial malformations leads to the development of cleft lip and cleft palate.

Genetics, Health, Science, Facial Malformations

3 points by gmays 37 days ago | 0 comments

All roses were once yellow (phys.org)
Red roses, the symbol of love, were likely yellow in the past, indicates a large genomic analysis by researchers from Beijing Forestry University, China.

Genetics, Botany, Evolution, China, Research

48 points by gmays 37 days ago | 6 comments

Metagenomics test saves woman's sight after mystery infection (bbc.co.uk)
A 29-year-old doctor from Bristol has had her eyesight saved after a "game-changing" test identified a mystery infection that had plagued her health for five years.

Medicine, Genetics, Science, Health

204 points by neversaydie 38 days ago | 80 comments

AI helps unravel a cause of Alzheimer’s and identify a therapeutic candidate (today.ucsd.edu)
A new study found that a gene recently recognized as a biomarker for Alzheimer’s disease is actually a cause of it, due to its previously unknown secondary function.

Alzheimer's Disease, Genetics, AI, Therapeutics

319 points by pedalpete 40 days ago | 160 comments

Eugenics is on the rise again: human geneticists must take a stand (nature.com)
In 1924, motivated by the rising eugenics movement, the United States passed the Johnson–Reed Act, which limited immigration to stem “a stream of alien blood, with all its inherited misconceptions”.

Eugenics, Genetics, History, Science, Ethics

14 points by geox 41 days ago | 1 comments