Hacker News with Generative AI: Medicine

Scientists discover new part of the immune system (bbc.com)
A new part of the immune system has been discovered and it is a goldmine of potential antibiotics, scientists have said.
Scientists crack how aspirin might stop cancers from spreading (bbc.com)
Scientists believe they have discovered how the cheap painkiller aspirin can stop cancers spreading.
Scientists discover new part of the immune system - potential for antibiotics (bbc.co.uk)
A new part of the immune system has been discovered and it is a goldmine of potential antibiotics, scientists have said.
Aspirin prevents metastasis by limiting TXA2 suppression of T cell immunity (nature.com)
Metastasis is the spread of cancer cells from primary tumours to distant organs and is the cause of 90% of cancer deaths globally1,2.
Gene therapy surgery restores some vision to legally blind children (newatlas.com)
Scientists in the UK have successfully used gene therapy to restore some vision to legally blind children with an inherited retinal condition.
Gene therapy surgery restores some vision to legally blind children (newatlas.com)
Scientists in the UK have successfully used gene therapy to restore some vision to legally blind children with an inherited retinal condition.
Surgery implants tooth material in eye as scaffolding for lens (cbc.ca)
When Brent Chapman’s doctor first pitched him on the idea of having one of his own teeth surgically embedded in his eye to restore his sight, he says he felt “a little apprehensive.”
When Professor Bryant Lin got cancer, he taught a class about it (nytimes.com)
Dr. Bryant Lin, who teaches medicine at Stanford University, was given a terminal diagnosis. He wanted his students to understand the humanity at the core of medicine.
Designing Self-Destructing Bacteria to Make Effective Tuberculosis Vaccines (weill.cornell.edu)
Working toward more effective tuberculosis (TB) vaccines, researchers at Weill Cornell Medicine have developed two strains of mycobacteria with "kill switches" that can be triggered to stop the bacteria after they activate an immune response.
Measles: The race to understand 'immune amnesia' (2024) (bbc.com)
Scientists have known for years that measles can alter the immune system – but the latest evidence suggests it's less of a mild tweaking, and more of a total reset.
CRISPR transforms ordinary fat cells into cancer killing machines (thebrighterside.news)
Scientists use CRISPR to turn fat cells into cancer-fighting machines, cutting off tumors’ nutrient supply and halting growth.
The quest for a "communication device" that tells cells to regenerate the body (bigthink.com)
What if medicine could harness this innate healing ability with precision, using technology to direct the body to repair damaged tissues and organs, or even regenerate them entirely?
One Head, Two Brains: The origins of split-brain research (2015) (theatlantic.com)
In 1939, a group of 10 people between the ages of 10 and 43, all with epilepsy, traveled to the University of Rochester Medical Center, where they would become the first people to undergo a radical new surgery.
Staphylococcus aureus 'steals' iron from our blood during infections (phys.org)
Researchers have revealed how Staphylococcus aureus bacteria extract iron from hemoglobin—a process crucial to their survival during infections.
Broken legs and ankles heal better if you walk on them within weeks (scientificamerican.com)
Twenty years ago my husband, Mark, broke his left ankle and was in a cast and on crutches for nearly two months. Last year he broke the other ankle. But this time, after surgery, his doctor surprised us by instructing Mark to walk on it two weeks later.
When Doctors with A.I. Are Outperformed by A.I. Alone (erictopol.substack.com)
A recent M.I.T.-Harvard study, of which one of us, Dr. Rajpurkar, is an author, examined how radiologists diagnose potential diseases from chest X-rays. The study found that when radiologists were shown A.I. predictions about the likelihood of disease, they often undervalued the A.I. input compared to their own judgment. The doctors stuck to their initial impressions even when the A.I. was correct, which led them to make less accurate diagnoses.
It's not just AI. China's medicines are surprising the world, too (economist.com)
It’s not just AI. China’s medicines are surprising the world, too
Scientists trace deadly cell-to-cell message chain that spreads in sepsis (phys.org)
Like a poison pen, dying cells prick their neighbors with a lethal message. This may worsen sepsis, Vijay Rathinam and colleagues in the UConn School of Medicine report in the Jan. 23 issue of Cell. Their findings could lead to a new understanding of this dangerous illness.
New obesity drugs are coming: these are the ones to watch (nature.com)
Dozens of new obesity drugs are coming: these are the ones to watch
Ozempic shows promise in reducing cravings for alcohol, heavy drinking (unchealthcare.org)
Dose-dependent effects of LSD in double-blind placebo-controlled study (2020) (nature.com)
Growing interest has been seen in using lysergic acid diethylamide (LSD) in psychiatric research and therapy.
Rethinking mental health: The body's impact on the brain (thetransmitter.org)
Psychiatric conditions have long been regarded as issues of “mental health,” a term that inherently ties our understanding of these disorders to the brain. But the brain does not exist in a vacuum. Growing evidence over the past 10 years highlights a link between the body and what we think of as mental health.
Cancer-fighting compound shows immense potential to eradicate HIV (news.stanford.edu)
The Physicians Are Healing Themselves, with Ozempic (nytimes.com)
At cardiology conferences and diabetes meetings, doctors can’t help noticing that thin seems to be very in.
The hallucinatory thoughts of the dying mind (mitpress.mit.edu)
Delirium is one of the most perplexing deathbed phenomena, exposing the gap between our cultural ideals of dying words and the reality of a disoriented mind.
Did UCLA Just Cure Baldness? (newsroom.ucla.edu)
UCLA scientists have now identified a small molecule that, when prompted, can waken long-slumbering but undamaged follicles.
AI tool helps find life-saving medicine for rare disease (pennmedicine.org)
After combing through 4,000 existing medications, an artificial intelligence tool helped uncover one that saved the life of a patient with idiopathic multicentric Castleman’s disease (iMCD).
You've Lost Weight Taking New Obesity Drugs. What Happens If You Stop? (nytimes.com)
Many patients are eager to discontinue Wegovy or Zepbound when their weight loss plateaus. But doctors say it’s difficult to go cold turkey.
Antibiotics, vaccinations linked to reduced risk of dementia (cam.ac.uk)
Antibiotics, antivirals, vaccinations and anti-inflammatory medication are associated with reduced risk of dementia, according to new research that looked at health data from over 130 million individuals.
FDA approves first new type of pain medication in 25 years (cnn.com)