Hacker News with Generative AI: Medicine

Weight-loss drug found to shrink muscle in mice, human cells (ualberta.ca)
Trendy weight-loss drugs making headlines for shrinking waistlines may also be shrinking the human heart and other muscles, according to a new University of Alberta study whose authors say should serve as a “cautionary tale” about possible long-term health effects of these drugs.
Health, Science, Medicine, Weight Loss, Drugs
230 points by Eumenes 9 hours ago | 246 comments
Ozempic Could Prevent Diabetes. Should It Be Used for That? (nytimes.com)
New research shows that weight loss medications can stop the progression of prediabetes. Experts don’t all agree on such a use for the drugs.
Diabetes, Medicine, Health, Weight Loss
5 points by bookofjoe 20 hours ago | 3 comments
Designer cells 'reboot' immune system in 3 different autoimmune diseases (livescience.com)
Biotechnology, Medicine, Immunology, Autoimmune Diseases
5 points by geox 1 day ago | 0 comments
'Achilles heel' of antibiotic-resistant bacteria discovered (studyfinds.org)
SAN DIEGO — In the ongoing battle against antibiotic-resistant “superbugs,” researchers have uncovered an unexpected vulnerability that could change how we fight these deadly infections – and it all comes down to a microscopic competition for resources.
Antibiotic Resistance, Microbiology, Science, Medicine
29 points by Brajeshwar 2 days ago | 5 comments
Vaccine shows promise against aggressive breast cancer (medicine.washu.edu)
A small clinical trial shows promising results for patients with triple-negative breast cancer who received an investigational vaccine designed to prevent recurrence of tumors.
Cancer Research, Medicine, Vaccines, Breast Cancer
6 points by geox 7 days ago | 0 comments
1 Genomic Test Can Diagnose Nearly Any Infection (ucsf.edu)
A genomic test developed at UC San Francisco to rapidly detect almost any kind of pathogen – virus, bacteria, fungus or parasite – has proved successful after a decade of use.
Genomics, Medicine, Infectious Diseases, Healthcare, Research
11 points by geox 7 days ago | 1 comments
Genetically engineered cellular nanoparticles for biomedical applications (2023) (nlm.nih.gov)
In recent years, nanoparticles derived from cellular membranes have been increasingly explored for the prevention and treatment of human disease.
Biotechnology, Nanomaterials, Medicine, Cellular Engineering
13 points by lawrenceyan 10 days ago | 1 comments
The Soul in the Stomach (2021) (wellcomecollection.org)
Sometime in the first half of the 17th century, the alchemist and physician Jan Baptist van Helmont (1580–1644) was spending a fairly typical day in his laboratory conducting experiments on wolfsbane – a highly toxic flower sometimes called the ‘queen of poisons’ – when he was called away from his work to attend to some household business. Later that evening, he began to feel distinctly odd.
History, Science, Medicine
24 points by yamrzou 11 days ago | 3 comments
The brain summons deep sleep for healing from life-threatening injury (nature.com)
Immune cells rush to the brain and promote deep sleep after a heart attack, according to a new study1 involving both mice and humans.
Neuroscience, Medicine, Sleep, Heart Attacks
365 points by gmays 11 days ago | 245 comments
Study reveals superbug MRSA's double defense against antibiotics (phys.org)
Scientists have discovered the mechanism which allows the superbug methicillin resistant Staphylococcus aureus (MRSA) to become highly resistant to antibiotics, paving the way for new approaches to control infectious disease.
Antibiotics, Superbugs, Microbiology, Medicine, Science
10 points by gmays 12 days ago | 0 comments
Paracelsus: Revolutionary or Mystic? (historytoday.com)
An enfant terrible shook up Renaissance medicine by denouncing experts and debunking accepted wisdom. Was Paracelsus as radical as he seemed?
Renaissance, Medicine, History, Science
6 points by drdee 14 days ago | 7 comments
Richard A. Cash, who saved millions from dehydration, has died (nytimes.com)
Richard A. Cash, who as a young public-health researcher in South Asia in the late 1960s showed that a simple cocktail of salt, sugar and clean water could check the ravages of cholera and other diarrhea-inducing diseases, an innovation that has saved an estimated 50 million lives, died on Oct. 22 at his home in Cambridge, Mass. He was 83.
Public Health, Medicine, Cholera, Disease Treatment, Obituary
198 points by impish9208 14 days ago | 53 comments
Scientists glue two proteins together, driving cancer cells to self-destruct (med.stanford.edu)
Stanford researchers hope new technique will flip lymphoma protein’s normal action — from preventing cell death to triggering it.
Cancer, Biology, Medicine, Research, Stanford
703 points by Jerry2 17 days ago | 178 comments
Researchers are questioning if ADHD should be seen as a disorder (economist.com)
Researchers are questioning if ADHD should be seen as a disorder
Health, Neurodiversity, Psychology, Medicine
29 points by uxhacker 20 days ago | 39 comments
From molecule to medicine, with Ross Rheingans-Yoo (complexsystemspodcast.com)
What happens between academic research and patients getting access to new drugs, and how we can improve it.
Medicine, Healthcare, Research, Science, Podcasts
7 points by tosh 20 days ago | 1 comments
Study illuminates how turncoat T cells launch nervous system assaults in MS (medicalxpress.com)
Few autoimmune disorders are more challenging for patients than multiple sclerosis, a progressive condition that can affect vision, impair the ability to walk, cause extreme bouts of neuropathic pain, and tends to strike women at three times the rate of men.
Multiple Sclerosis, Autoimmune Disorders, Neuroscience, Medicine, Health
4 points by wglb 21 days ago | 0 comments
GLP-1s are among the most important drug breakthroughs (economist.com)
IN THE HISTORY of medicine, a few drugs tower above all others. Humira for rheumatoid arthritis; Prozac for depression; statins to prevent heart disease and strokes. All have helped patients far beyond doctors’ initial expectations and continue to benefit millions of people every day. A new class of drugs is set to join their ranks and has the potential to eclipse them all—GLP-1 receptor agonists.
Pharmaceuticals, Medicine, Health, Science, Drugs
58 points by car 22 days ago | 147 comments
Family medicine is in decline (thewalrus.ca)
Why family medicine is dying
Health, Medicine, Healthcare, Family Medicine
88 points by mooreds 24 days ago | 209 comments
New study finds obesity operations dropped 25.6% in 2023 due to GLP-1 drugs (statnews.com)
For people with obesity, surgeries that shrink, reshape, or otherwise alter the anatomy of the stomach have long reigned supreme as the surest way to weight loss. But in the last few years, with the approval of GLP-1 drugs like Wegovy and Zepbound, more and more people are opting for obesity medicines over gold-standard surgical treatments.
Obesity, Healthcare, Medicine, Pharmaceuticals, Weight Loss
6 points by ck2 25 days ago | 3 comments
Saturated fat: the making and unmaking of a scientific consensus (2022) (journals.lww.com)
The concept that saturated fat causes cardiovascular disease by raising serum cholesterol is called the ‘diet-heart hypothesis’, a highly influential idea that has been a lynchpin of nutrition policy for some 60 years.
Nutrition, Science, Health, Medicine
184 points by mgh2 26 days ago | 424 comments
Rapamycin and Anti-Aging: What to Know (nytimes.com)
In March, Robert Berger, 69, a self-proclaimed “better-living-through-chemistry type of person,” started taking a small dose of rapamycin once a week with the goal of increasing his “health span” — the amount of time he might live without serious disease.
Health, Anti-Aging, Medicine, Longevity
6 points by bookofjoe 26 days ago | 2 comments
Extra-uterine system to physiologically support the extreme premature lamb(2017) (nature.com)
In the developed world, extreme prematurity is the leading cause of neonatal mortality and morbidity due to a combination of organ immaturity and iatrogenic injury.
Medicine, Science, Premature Birth, Biology
4 points by sandwichsphinx 27 days ago | 1 comments
It's not just obesity. Drugs like Ozempic will change the world (economist.com)
Every day seems to bring more exciting news. First the drugs tackled diabetes. Then, with just an injection a week, they took on obesity. Now they are being found to treat cardiovascular and kidney disease, and are being tested for Alzheimer’s and addiction. It is early days yet, but glp-1 receptor agonists have all the makings of one of the most successful classes of drugs in history.
Health, Pharmaceuticals, Obesity, Medicine
32 points by Anon84 27 days ago | 167 comments
The brain's waste clearing lymphatic system shown in people for first time (nih.gov)
A study in five volunteers undergoing surgery confirmed the existence of channels that may help drain waste from the brain.
Neuroscience, Medicine, Biology, Research, Health
316 points by SubiculumCode 27 days ago | 105 comments
Exercise as an equivalent to medication for treatment of depression and anxiety (peterattiamd.com)
Popular media has touted a provocative claim that exercise is purportedly as effective as medication in treating symptoms of depression and anxiety.
Exercise, Mental Health, Depression, Anxiety, Medicine
30 points by mpweiher 32 days ago | 4 comments
A new artificial intelligence tool for cancer (hms.harvard.edu)
Cancer, Artificial Intelligence, Medicine, Health
114 points by mgh2 32 days ago | 48 comments
Why Surgeons Are Wearing the Apple Vision Pro in Operating Rooms (time.com)
Twenty-four years ago, the surgeon Santiago Horgan performed the first robotically assisted gastric-bypass surgery in the world, a major medical breakthrough. Now Horgan is working with a new tool that he argues could be even more transformative in operating rooms: the Apple Vision Pro.
Medicine, Surgery, Apple, Technology, Augmented Reality
95 points by williamstein 32 days ago | 80 comments
'Miracle' weight-loss drugs could lead to debilitating brittle bones, fractures (dailymail.co.uk)
Experts warn that 'miracle' weight-loss drugs could lead to fractures and brittle bones.
Health, Medicine, Weight Loss, Side Effects
9 points by LinuxBender 32 days ago | 3 comments
Promising new form of antibiotic that makes bacterial cells self-destruct (phys.org)
To address the global threat of antibiotic resistance, scientists are on the hunt for new ways to sneak past a bacterial cell's defense system.
Antibiotics, Science, Medicine, Bacterial Resistance
22 points by WaitWaitWha 33 days ago | 7 comments
Surgeons at UCSD Find Apple Vision Pro Promising for Minimally Invasive Surgery (macrumors.com)
Surgeons at the University of California, San Diego have been testing the Apple Vision Pro for surgeries, and have performed more than 20 minimally invasive operations while wearing the headsets.
Medicine, Technology, Augmented Reality, Apple
8 points by jinjin2 35 days ago | 3 comments