Hacker News with Generative AI: Clinical Trials

Progress and prospects of mRNA-based drugs in pre-clinical/clinical applications (nature.com)
In the last decade, messenger ribonucleic acid (mRNA)-based drugs have gained great interest in both immunotherapy and non-immunogenic applications.

mRNA Technology, Biomedicine, Drug Development, Clinical Trials, Medical Research

3 points by lawrenceyan 3 days ago | 0 comments

Psilocybin bests SSRI for major depression in first long-term comparison (medscape.com)

Psilocybin, Depression, Mental Health, Pharmaceuticals, Clinical Trials

582 points by Thomvis 40 days ago | 379 comments

Rwanda to receive experimental vaccines to combat Marburg outbreak (statnews.com)
Experimental vaccines and therapeutics to combat the deadly Marburg virus will begin arriving this weekend in Rwanda, where they will be used in clinical trials expected to begin soon, a U.S. government official confirmed on Friday.

Vaccines, Public Health, Africa, Viral Outbreaks, Clinical Trials

4 points by geox 47 days ago | 0 comments

mRNA cancer vaccine shows potential for advanced stage cancer patients (kcl.ac.uk)
Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.

Cancer, Vaccines, Clinical Trials, Immunotherapy

13 points by nopakos 65 days ago | 0 comments

Gilead's twiceyearly shot cut HIV infections by 96% in trial (cnbc.com)

HIV, Medicine, Health, Clinical Trials

4 points by jackallis 70 days ago | 0 comments

Epilepsy drug shows promise in reducing obstructive sleep apnea symptoms (ajmc.com)
Sulthiame, an epilepsy drug sold under the brand name Ospolot in Europe, appeared to reduce symptoms of obstructive sleep apnea (OSA) in a late-breaking clinical trial presented at the European Respiratory Society (ERS) Congress 2024.

Medicine, Sleep Disorders, Clinical Trials, Epilepsy

7 points by geox 72 days ago | 0 comments

World-first lung cancer vaccine trials launched across seven countries (theguardian.com)

Lung Cancer, Medical Research, Vaccines, Clinical Trials

29 points by doener 81 days ago | 1 comments

World-first mRNA lung cancer vaccine trials launched in seven countries (theguardian.com)

Cancer, Healthcare, Science, Clinical Trials, Vaccines

12 points by NKosmatos 90 days ago | 0 comments

New HIV Prevention Drug Shows 100% Efficacy in Clinical Trial (sciencealert.com)

HIV, Medicine, Health, Clinical Trials

37 points by doener 129 days ago | 2 comments

Gilead shot prevents all HIV cases in trial (bloomberg.com)