Hacker News with Generative AI: Drugs

Weight-loss drug found to shrink heart muscle in mice, human cells (ualberta.ca)
Trendy weight-loss drugs making headlines for shrinking waistlines may also be shrinking the human heart and other muscles, according to a new University of Alberta study whose authors say should serve as a “cautionary tale” about possible long-term health effects of these drugs.

Health, Weight Loss, Medical Research, Drugs, Science

213 points by Eumenes 8 hours ago | 238 comments

GLP-1s are among the most important drug breakthroughs (economist.com)
IN THE HISTORY of medicine, a few drugs tower above all others. Humira for rheumatoid arthritis; Prozac for depression; statins to prevent heart disease and strokes. All have helped patients far beyond doctors’ initial expectations and continue to benefit millions of people every day. A new class of drugs is set to join their ranks and has the potential to eclipse them all—GLP-1 receptor agonists.

Pharmaceuticals, Medicine, Health, Science, Drugs

58 points by car 22 days ago | 147 comments

Psychedelic Mushrooms Are Getting Much, Much Stronger (wired.com)
Cultivators are turning to genetic sequencing and cellular-manipulation techniques to breed highly potent mushrooms—leaving some unprepared psychonauts in distress.

Psychedelics, Science, Drugs, Genetics

7 points by bookofjoe 40 days ago | 12 comments

On 17th century "cocaine" (resobscura.substack.com)
Earlier this year, amid a sea of bones in the vaulted crypt beneath Milan’s Ca’ Granda hospital, Italian researchers made an intriguing discovery. Analyzing mummified brain tissue from two men who died at the hospital in the seventeenth century, they found evidence of coca use—the earliest ever detected outside of South America.

History, Archaeology, Drugs, Italy

161 points by benbreen 43 days ago | 209 comments

Science Says Everything You Know about Food, Diet and Drugs Is Wrong (newsweek.com)
Science can't provide definitive answers.

Science, Nutrition, Health, Diet, Drugs

3 points by paulpauper 57 days ago | 0 comments

Scientists Discover 17th Century Bones Contained Cocaine (popularmechanics.com)
The surprising discovery reveals Europeans sniffed around much earlier than we thought.

Archaeology, History, Drugs, Cocaine

6 points by gmays 73 days ago | 0 comments

Forensic toxicology backdates the use of coca plant in Europe to the early 1600s (sciencedirect.com)

Forensic Science, History, Drugs, Europe

30 points by benbreen 84 days ago | 5 comments

From Opium to Saffron, the Ancients Knew a Thing or Two About Drugs (thenation.com)

History, Drugs, Ancient History, Culture

43 points by NoRagrets 87 days ago | 15 comments

HIV drug could be made for just $40 a year for every patient (theguardian.com)

HIV, Healthcare, Cost, Medicine, Drugs

66 points by nithinj 103 days ago | 88 comments

If Fever Helps Fight Infection, Should I Avoid Fever-Reducing Drugs? (2018) (nytimes.com)

Health, Medicine, Fever, Infection, Drugs

45 points by doener 106 days ago | 37 comments

Meta allows drug ads selling everything from opioids to cocaine (techtransparencyproject.org)

Meta, Advertising, Drugs, Social Media, Regulation

19 points by geox 106 days ago | 1 comments

I Wasn't the First Person to Find the NJ Coca-Cola Cocaine Factory (2016) (medium.com)

History, New Jersey, Coca-Cola, Drugs

83 points by kome 109 days ago | 7 comments

Meta has run hundreds of ads for cocaine, opioids and other drugs (wsj.com)

Meta, Advertising, Drugs, Social Media

171 points by cwwc 113 days ago | 215 comments

Cocaine found in muscle/liver of sharpnose sharks off coast of Rio de Janeiro (phys.org)

Cocaine, Sharks, Brazil, Drugs, Marine Biology

11 points by wglb 114 days ago | 1 comments

We bought everything needed to make $3M worth of fentanyl (reuters.com)

Fentanyl, Drugs, Crime, News

27 points by tmslnz 119 days ago | 6 comments

MPPP – The first 'designer drug' disaster (2023) (bris.ac.uk)

Drugs, History, Public Health, Science

160 points by aragonite 120 days ago | 187 comments

Sharks test positive for cocaine in waters off Brazilian coast (thetimes.com)

Drugs, Environment, Brazil, Sharks, Wildlife

32 points by pelagicAustral 121 days ago | 25 comments

A scientist took a psychedelic drug – and watched his own brain 'fall apart' (npr.org)

Science, Neuroscience, Psychedelics, Drugs

10 points by helsinkiandrew 125 days ago | 1 comments

Mexico may legalize magic mushrooms (latimes.com)

Mexico, Psychedelics, Law, Drugs

4 points by chapulin 143 days ago | 0 comments

Synthetic psychedelic found in candies linked to seizures, intubation (arstechnica.com)

Drugs, Health, Science, Safety

13 points by bikenaga 147 days ago | 5 comments

Tripping on Xenon Gas (2023) (tripsitter.substack.com)

Drugs, Health, Psychedelics, Substack

133 points by rajlego 147 days ago | 186 comments

Bugs, drugs and electric venom: is this the most deadly library in the world? (theguardian.com)

Libraries, Danger, Toxicity, Drugs, Venom

13 points by markx2 152 days ago | 0 comments

FDA Panel rejects MDMA as a PTSD treatment in possible setback for advocates (apnews.com)

FDA, Mental Health, PTSD, Drugs, Medical Research

12 points by rendx 169 days ago | 9 comments

Ask HN: Have you tried weight loss drugs? (ycombinator.com)

Health, Weight Loss, Personal Experience, Drugs

15 points by slayerjain 179 days ago | 48 comments

Outlaw chemists used 'blotter' to dose the world with LSD Essays (aeon.co)

Drugs, History, Culture, Science

26 points by rbanffy 195 days ago | 3 comments

British Columbia to recriminalize use of drugs in public spaces (cbc.ca)

Drugs, Law Enforcement, British Columbia, Public Health

239 points by Kairon 208 days ago | 439 comments

Why Alcohol Is the Deadliest Drug (addictioncenter.com)

Alcohol, Addiction, Health, Drugs

32 points by doener 218 days ago | 35 comments