Hacker News with Generative AI: Obesity

Fat cells have 'memory' of obesity – hinting at why it's hard to keep weight off (nature.com)
Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity, research1 shows — a finding that might help to explain why it can be hard to stay trim after a weight-loss programme.

Obesity, Biology, Health, Weight Loss

12 points by bookofjoe 1 day ago | 0 comments

Fat cells have a 'memory' of obesity – why it's hard to keep weight off (nature.com)
Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity, research1 shows — a finding that might help to explain why it can be hard to stay trim after a weight-loss programme.

Obesity, Health, Science, Biology

11 points by Brajeshwar 2 days ago | 0 comments

Three-Quarters of U.S. Adults Are Now Overweight or Obese (nytimes.com)
Nearly three quarters of U.S. adults are overweight or obese, according to a sweeping new study.

Health, Obesity, Statistics, United States

50 points by JumpCrisscross 6 days ago | 158 comments

Weight-loss surgery down 25 percent as anti-obesity drug use soars (news.harvard.edu)
A new study examining a large sample of privately insured patients with obesity found that use of drugs such as Ozempic and Wegovy as anti-obesity medications more than doubled from 2022 to 2023.

Obesity, Healthcare, Pharmaceuticals, Weight Loss

11 points by paulpauper 22 days ago | 1 comments

New study finds obesity operations dropped 25.6% in 2023 due to GLP-1 drugs (statnews.com)
For people with obesity, surgeries that shrink, reshape, or otherwise alter the anatomy of the stomach have long reigned supreme as the surest way to weight loss. But in the last few years, with the approval of GLP-1 drugs like Wegovy and Zepbound, more and more people are opting for obesity medicines over gold-standard surgical treatments.

Obesity, Healthcare, Medicine, Pharmaceuticals, Weight Loss

6 points by ck2 25 days ago | 3 comments

It's not just obesity. Drugs like Ozempic will change the world (economist.com)
Every day seems to bring more exciting news. First the drugs tackled diabetes. Then, with just an injection a week, they took on obesity. Now they are being found to treat cardiovascular and kidney disease, and are being tested for Alzheimer’s and addiction. It is early days yet, but glp-1 receptor agonists have all the makings of one of the most successful classes of drugs in history.

Health, Pharmaceuticals, Obesity, Medicine

32 points by Anon84 27 days ago | 167 comments

In Good Health: Weight Loss Drugs and the Falling Obesity Rate (npr.org)
For the first time in decades, obesity rates in the U.S. are not on the rise.

Health, Obesity, Public Health, Medicine, Statistics

5 points by paulpauper 36 days ago | 1 comments

Study: Access to high-speed internet is associated with increased obesity (sciencedirect.com)
We examine the impact of access to high-speed internet on obesity.

Health, Internet Access, Obesity, Research, Social Impact

4 points by giuliomagnifico 37 days ago | 0 comments

Unemployed could get weight loss jabs to return to work (bbc.com)
Proposals to give weight loss jabs to unemployed people living with obesity could be "very important" for our economy and health, the prime minister has told the BBC.

Health, Economics, Obesity, Employment

3 points by Eumenes 37 days ago | 1 comments

How long til we're all on Ozempic? (asteriskmag.com)
Over 100 million Americans, and possibly many more, could benefit from GLP-1 drugs. When can they expect to get them?

Health, Pharmaceuticals, Obesity, Medicine

461 points by thehoff 41 days ago | 1584 comments

GLP-1 agonists (Wegovy, Ozempic,) cause disproportionate muscle loss (ft.com)

Health, Pharmaceuticals, Weight Loss, Obesity

4 points by hilux 46 days ago | 3 comments

Fenfluramine/Phentermine (wikipedia.org)
The drug combination fenfluramine/phentermine, usually called fen-phen, is an anti-obesity medication that is no longer widely available.

Medicine, Pharmaceuticals, Obesity, Health, History

8 points by kamaraju 53 days ago | 3 comments

Obesity is driven by a build-up of molecular mesh around hunger neurons (nature.com)
The accumulation of a network of proteins and sugars called the extracellular matrix stops insulin from reaching hunger-regulating neurons, disrupting normal food intake and metabolism, and contributing to obesity.

Obesity, Neuroscience, Biology, Metabolism, Cellular Biology

3 points by bookofjoe 63 days ago | 1 comments

Why People Are Breaking Open Their Mounjaro Pens (theatlantic.com)

Health, Pharmaceuticals, Medical Devices, Obesity

16 points by mooreds 73 days ago | 2 comments

Ozempic maker defends high U.S. price: It's 'helping' reduce the cost of obesity (nbcnews.com)

Pharmaceuticals, Healthcare, Obesity, Pricing

10 points by heavyset_go 86 days ago | 14 comments

GLP-1 therapy increases visceral adipose tissue metabolic activity (wiley.com)

GLP-1 therapy, Metabolism, Health, Obesity, Visceral Fat

105 points by gumby 90 days ago | 118 comments

More People Are Overdosing on Ozempic Alternatives (nytimes.com)