Hacker News with Generative AI: Obesity

Why is the American diet so deadly? (newyorker.com)
Food scientists are investigating a possible cause of the obesity epidemic which wasn’t named until the twenty-first century: ultra-processed foods.
As obesity skyrockets, Dietary Guidelines go from pro-vegetable to anti-meat (uncertaintyprinciples.substack.com)
As obesity rates skyrocket, Dietary Guidelines go from being pro-vegetable to anti-meat. How'd that happen?
Pfizer Stopped Us from Getting Ozempic Decades Ago (nytimes.com)
They called 2023 the year of Ozempic, but it now seems GLP-1 drugs might define an entire decade — or an even longer era.
The strange link between obesity and corruption (bigthink.com)
Corruption makes you fat — that’s the hypothesis behind a creative study that compared body mass index (BMI) with conventional measures of corruption in post-Soviet countries.
Obesity is down in the US in a decade (bloomberg.com)
Obesity is down in the US for the first time in a decade. A new study suggests weight-loss drugs may explain why.
Being overweight overtakes tobacco smoking as the leading disease risk factor (scimex.org)
Living with overweight or obesity has overtaken tobacco smoking as the leading risk factor contributing to disease burden in 2024, according to a new report from the Australian Institute of Health and Welfare.
Social drinkers on obesity drugs lose the taste for alcohol (npr.org)
Many social drinkers who take obesity medications, such as Wegovy or Mounjaro, say they don't enjoy alcohol as much.
208 million Americans are classified as obese or overweight (theconversation.com)
Nearly half of adolescents and three-quarters of adults in the U.S. were classified as being clinically overweight or obese in 2021. The rates have more than doubled compared with 1990.
Fat Cells Remember Obesity, Driving the Yo-Yo Effect (technologynetworks.com)
Researchers uncover how epigenetic memory in fat cells drives the yo-yo effect, making weight regain more likely.
Fat cells have a memory of obesity – hinting at why it's hard to keep weight off (nature.com)
Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity, research1 shows — a finding that might help to explain why it can be hard to stay trim after a weight-loss programme.
Fat cells have 'memory' of obesity – hinting at why it's hard to keep weight off (nature.com)
Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity, research1 shows — a finding that might help to explain why it can be hard to stay trim after a weight-loss programme.
Fat cells have a 'memory' of obesity – why it's hard to keep weight off (nature.com)
Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity, research1 shows — a finding that might help to explain why it can be hard to stay trim after a weight-loss programme.
Three-Quarters of U.S. Adults Are Now Overweight or Obese (nytimes.com)
Nearly three quarters of U.S. adults are overweight or obese, according to a sweeping new study.
Weight-loss surgery down 25 percent as anti-obesity drug use soars (news.harvard.edu)
A new study examining a large sample of privately insured patients with obesity found that use of drugs such as Ozempic and Wegovy as anti-obesity medications more than doubled from 2022 to 2023.
New study finds obesity operations dropped 25.6% in 2023 due to GLP-1 drugs (statnews.com)
For people with obesity, surgeries that shrink, reshape, or otherwise alter the anatomy of the stomach have long reigned supreme as the surest way to weight loss. But in the last few years, with the approval of GLP-1 drugs like Wegovy and Zepbound, more and more people are opting for obesity medicines over gold-standard surgical treatments.
It's not just obesity. Drugs like Ozempic will change the world (economist.com)
Every day seems to bring more exciting news. First the drugs tackled diabetes. Then, with just an injection a week, they took on obesity. Now they are being found to treat cardiovascular and kidney disease, and are being tested for Alzheimer’s and addiction. It is early days yet, but glp-1 receptor agonists have all the makings of one of the most successful classes of drugs in history.
In Good Health: Weight Loss Drugs and the Falling Obesity Rate (npr.org)
For the first time in decades, obesity rates in the U.S. are not on the rise.
Study: Access to high-speed internet is associated with increased obesity (sciencedirect.com)
We examine the impact of access to high-speed internet on obesity.
Unemployed could get weight loss jabs to return to work (bbc.com)
Proposals to give weight loss jabs to unemployed people living with obesity could be "very important" for our economy and health, the prime minister has told the BBC.
How long til we're all on Ozempic? (asteriskmag.com)
Over 100 million Americans, and possibly many more, could benefit from GLP-1 drugs. When can they expect to get them?
GLP-1 agonists (Wegovy, Ozempic,) cause disproportionate muscle loss (ft.com)
Fenfluramine/Phentermine (wikipedia.org)
The drug combination fenfluramine/phentermine, usually called fen-phen, is an anti-obesity medication that is no longer widely available.
Obesity is driven by a build-up of molecular mesh around hunger neurons (nature.com)
The accumulation of a network of proteins and sugars called the extracellular matrix stops insulin from reaching hunger-regulating neurons, disrupting normal food intake and metabolism, and contributing to obesity.
Why People Are Breaking Open Their Mounjaro Pens (theatlantic.com)
Ozempic maker defends high U.S. price: It's 'helping' reduce the cost of obesity (nbcnews.com)
GLP-1 therapy increases visceral adipose tissue metabolic activity (wiley.com)
More People Are Overdosing on Ozempic Alternatives (nytimes.com)
What Happens When Ozempic Takes over Your Town (bloomberg.com)
Weight-loss power of oats naturally mimics popular obesity drugs (newatlas.com)
Ozempic Settles the Obesity Debate: It's Biology over Willpower (wsj.com)