Hacker News with Generative AI: Obesity

Hotdogs and motorways: The ripples created by Denmark's Ozempic and Wegovy boom (bbc.com)
American demand for weight-loss drugs is supercharging Denmark’s economy and transforming a small Danish community into an unlikely boomtown.

Economy, Healthcare, Denmark, Pharmaceuticals, Obesity

6 points by PotatoNinja 12 hours ago | 0 comments

New obesity drugs are coming: these are the ones to watch (nature.com)
Dozens of new obesity drugs are coming: these are the ones to watch

Medicine, Health, Pharmaceuticals, Obesity

5 points by sohkamyung 8 days ago | 0 comments

% Obesity by Country Ranking (worldobesity.org)
Prevalence of obesity (BMI ≥ 30kg/m²)

Health, Statistics, World Data, Obesity

9 points by melenaboija 10 days ago | 0 comments

The Physicians Are Healing Themselves, with Ozempic (nytimes.com)
At cardiology conferences and diabetes meetings, doctors can’t help noticing that thin seems to be very in.

Health, Medicine, Obesity, Weight Loss, Pharmaceuticals

43 points by CharlesW 11 days ago | 86 comments

You've Lost Weight Taking New Obesity Drugs. What Happens If You Stop? (nytimes.com)
Many patients are eager to discontinue Wegovy or Zepbound when their weight loss plateaus. But doctors say it’s difficult to go cold turkey.

Obesity, Weight Loss, Health, Medicine, Science

7 points by paulpauper 18 days ago | 0 comments

Weight-loss surgery down 25 percent as anti-obesity drug use soars (2024) (news.harvard.edu)
A new study examining a large sample of privately insured patients with obesity found that use of drugs such as Ozempic and Wegovy as anti-obesity medications more than doubled from 2022 to 2023. During that same period, there was a 25.6 percent decrease in patients undergoing metabolic bariatric surgery to treat obesity.

Weight Loss, Medical Treatments, Pharmaceuticals, Healthcare, Obesity

7 points by paulpauper 24 days ago | 1 comments

Obesity drugs: study highlights new health risks (nature.com)
Blockbuster obesity drugs such as Ozempic have been celebrated for their ability to treat weight loss and a surprising range of other conditions, from heart issues to Parkinson’s disease. Now, an analysis of data from nearly 2 million people is revealing new insights into the effects of these medications — including the risks they pose.

Health, Medicine, Obesity, Science

21 points by rbanffy 32 days ago | 4 comments

Why is the American diet so deadly? (newyorker.com)
Food scientists are investigating a possible cause of the obesity epidemic which wasn’t named until the twenty-first century: ultra-processed foods.

Food, Health, Diet, Obesity, Food Science

79 points by johnkpaul 45 days ago | 184 comments

As obesity skyrockets, Dietary Guidelines go from pro-vegetable to anti-meat (uncertaintyprinciples.substack.com)
As obesity rates skyrocket, Dietary Guidelines go from being pro-vegetable to anti-meat. How'd that happen?

Health, Nutrition, Food Policy, Obesity

7 points by hilux 54 days ago | 7 comments

Pfizer Stopped Us from Getting Ozempic Decades Ago (nytimes.com)
They called 2023 the year of Ozempic, but it now seems GLP-1 drugs might define an entire decade — or an even longer era.

Pharmaceuticals, Health, Obesity, Medical Research

15 points by bko 57 days ago | 2 comments

The strange link between obesity and corruption (bigthink.com)
Corruption makes you fat — that’s the hypothesis behind a creative study that compared body mass index (BMI) with conventional measures of corruption in post-Soviet countries.

Obesity, Corruption, Science, Social Studies, Health

15 points by ____H____ 62 days ago | 3 comments

Obesity is down in the US in a decade (bloomberg.com)
Obesity is down in the US for the first time in a decade. A new study suggests weight-loss drugs may explain why.

Obesity, Health, Public Health, United States, Medical Research

6 points by JumpCrisscross 70 days ago | 1 comments

Being overweight overtakes tobacco smoking as the leading disease risk factor (scimex.org)
Living with overweight or obesity has overtaken tobacco smoking as the leading risk factor contributing to disease burden in 2024, according to a new report from the Australian Institute of Health and Welfare.

Health, Public Health, Obesity, Smoking, Australia

317 points by giuliomagnifico 72 days ago | 347 comments

Social drinkers on obesity drugs lose the taste for alcohol (npr.org)
Many social drinkers who take obesity medications, such as Wegovy or Mounjaro, say they don't enjoy alcohol as much.

Obesity, Alcohol, Health, Science, Medications

15 points by pseudolus 81 days ago | 14 comments

208 million Americans are classified as obese or overweight (theconversation.com)
Nearly half of adolescents and three-quarters of adults in the U.S. were classified as being clinically overweight or obese in 2021. The rates have more than doubled compared with 1990.

Health, Obesity, United States

4 points by geox 82 days ago | 2 comments

Fat Cells Remember Obesity, Driving the Yo-Yo Effect (technologynetworks.com)
Researchers uncover how epigenetic memory in fat cells drives the yo-yo effect, making weight regain more likely.

Obesity, Health, Genetics, Epigenetics, Weight Loss

5 points by gmays 88 days ago | 1 comments

Fat cells have a memory of obesity – hinting at why it's hard to keep weight off (nature.com)
Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity, research1 shows — a finding that might help to explain why it can be hard to stay trim after a weight-loss programme.

Obesity, Weight Loss, Biology, Health, Science

8 points by SirLJ 89 days ago | 0 comments

Fat cells have 'memory' of obesity – hinting at why it's hard to keep weight off (nature.com)
Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity, research1 shows — a finding that might help to explain why it can be hard to stay trim after a weight-loss programme.

Obesity, Biology, Health, Weight Loss

12 points by bookofjoe 94 days ago | 0 comments

Fat cells have a 'memory' of obesity – why it's hard to keep weight off (nature.com)
Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity, research1 shows — a finding that might help to explain why it can be hard to stay trim after a weight-loss programme.

Obesity, Health, Science, Biology

11 points by Brajeshwar 94 days ago | 0 comments

Three-Quarters of U.S. Adults Are Now Overweight or Obese (nytimes.com)
Nearly three quarters of U.S. adults are overweight or obese, according to a sweeping new study.

Health, Obesity, Statistics, United States

50 points by JumpCrisscross 98 days ago | 158 comments

Weight-loss surgery down 25 percent as anti-obesity drug use soars (news.harvard.edu)
A new study examining a large sample of privately insured patients with obesity found that use of drugs such as Ozempic and Wegovy as anti-obesity medications more than doubled from 2022 to 2023.

Obesity, Healthcare, Pharmaceuticals, Weight Loss

11 points by paulpauper 115 days ago | 1 comments

New study finds obesity operations dropped 25.6% in 2023 due to GLP-1 drugs (statnews.com)
For people with obesity, surgeries that shrink, reshape, or otherwise alter the anatomy of the stomach have long reigned supreme as the surest way to weight loss. But in the last few years, with the approval of GLP-1 drugs like Wegovy and Zepbound, more and more people are opting for obesity medicines over gold-standard surgical treatments.

Obesity, Healthcare, Medicine, Pharmaceuticals, Weight Loss

6 points by ck2 117 days ago | 3 comments

It's not just obesity. Drugs like Ozempic will change the world (economist.com)
Every day seems to bring more exciting news. First the drugs tackled diabetes. Then, with just an injection a week, they took on obesity. Now they are being found to treat cardiovascular and kidney disease, and are being tested for Alzheimer’s and addiction. It is early days yet, but glp-1 receptor agonists have all the makings of one of the most successful classes of drugs in history.

Health, Pharmaceuticals, Obesity, Medicine

32 points by Anon84 119 days ago | 167 comments

In Good Health: Weight Loss Drugs and the Falling Obesity Rate (npr.org)
For the first time in decades, obesity rates in the U.S. are not on the rise.

Health, Obesity, Public Health, Medicine, Statistics

5 points by paulpauper 129 days ago | 1 comments

Study: Access to high-speed internet is associated with increased obesity (sciencedirect.com)
We examine the impact of access to high-speed internet on obesity.

Health, Internet Access, Obesity, Research, Social Impact

4 points by giuliomagnifico 129 days ago | 0 comments

Unemployed could get weight loss jabs to return to work (bbc.com)
Proposals to give weight loss jabs to unemployed people living with obesity could be "very important" for our economy and health, the prime minister has told the BBC.

Health, Economics, Obesity, Employment

3 points by Eumenes 129 days ago | 1 comments

How long til we're all on Ozempic? (asteriskmag.com)
Over 100 million Americans, and possibly many more, could benefit from GLP-1 drugs. When can they expect to get them?

Health, Pharmaceuticals, Obesity, Medicine

461 points by thehoff 133 days ago | 1584 comments

GLP-1 agonists (Wegovy, Ozempic,) cause disproportionate muscle loss (ft.com)

Health, Pharmaceuticals, Weight Loss, Obesity

4 points by hilux 138 days ago | 3 comments

Fenfluramine/Phentermine (wikipedia.org)
The drug combination fenfluramine/phentermine, usually called fen-phen, is an anti-obesity medication that is no longer widely available.

Medicine, Pharmaceuticals, Obesity, Health, History

8 points by kamaraju 146 days ago | 3 comments

Obesity is driven by a build-up of molecular mesh around hunger neurons (nature.com)
The accumulation of a network of proteins and sugars called the extracellular matrix stops insulin from reaching hunger-regulating neurons, disrupting normal food intake and metabolism, and contributing to obesity.

Obesity, Neuroscience, Biology, Metabolism, Cellular Biology

3 points by bookofjoe 155 days ago | 1 comments