Hacker News with Generative AI: Medical Research

Weight-loss drug found to shrink heart muscle in mice, human cells (ualberta.ca)
Trendy weight-loss drugs making headlines for shrinking waistlines may also be shrinking the human heart and other muscles, according to a new University of Alberta study whose authors say should serve as a “cautionary tale” about possible long-term health effects of these drugs.
Health, Weight Loss, Medical Research, Drugs, Science
208 points by Eumenes 7 hours ago | 234 comments
Progress and prospects of mRNA-based drugs in pre-clinical/clinical applications (nature.com)
In the last decade, messenger ribonucleic acid (mRNA)-based drugs have gained great interest in both immunotherapy and non-immunogenic applications.
mRNA Technology, Biomedicine, Drug Development, Clinical Trials, Medical Research
3 points by lawrenceyan 2 days ago | 0 comments
Severe Covid-19 may shrink cancer tumors, early data suggest (livescience.com)
COVID-19, Cancer, Medical Research, Health
4 points by amichail 3 days ago | 1 comments
Australian scientists thought to be on the verge of curing paralysis (9news.com.au)
Australian scientists believe they are on the verge of uncovering the cure for paralysis, with world-first trials set to use nerve cells from the nose to treat patients.
Australia, Science, Medical Research, Paralysis
16 points by doener 10 days ago | 0 comments
Scientist treated her own cancer with viruses she grew in the lab (nature.com)
A scientist who successfully treated her own breast cancer by injecting the tumour with lab-grown viruses has sparked discussion about the ethics of self-experimentation.
Cancer Treatment, Medical Research, Ethics
692 points by dataminer 12 days ago | 248 comments
Genetic repair via CRISPR can inadvertently introduce other defects (phys.org)
The CRISPR molecular scissors have the potential to revolutionize the treatment of genetic diseases. This is because they can be used to correct specific defective sections of the genome. Unfortunately, however, there is a catch: under certain conditions, the repair can lead to new genetic defects—as in the case of chronic granulomatous disease.
Genetics, CRISPR, Medical Research
111 points by amichail 13 days ago | 65 comments
A 'Crazy' Idea for Treating Autoimmune Diseases Might Work (theatlantic.com)
Lupus has long been considered incurable—but a series of breakthroughs are fueling hope.
Autoimmune Diseases, Medical Research, Health, Lupus
12 points by aarghh 16 days ago | 1 comments
Antibody Drug Conjugates: A frontier in cancer treatment (sagelyhealth.com)
An exciting frontier in cancer treatment over 100 years in the making.
Cancer, Medical Research, Pharmaceuticals, Biotechnology, Treatment
107 points by peerless-app 21 days ago | 44 comments
1374 Days – My Journey with Long Covid (2023) (giorgialupi.com)
For more than three years I’ve been suffering with a debilitating, chronic illness most people call Long Covid.
Long COVID, Health, Personal Experiences, Chronic Illness, Medical Research
87 points by simonebrunozzi 21 days ago | 112 comments
Research reveals new clues to the mysteries of long Covid (ualberta.ca)
Researchers at the University of Alberta have pinpointed two proteins that could serve as markers for identifying patients with long COVID — a discovery that may lead to treatments that will bring better quality of life for the millions of people suffering from the debilitating condition.
Medical Research, COVID-19, Health, Science
33 points by amichail 23 days ago | 5 comments
Survival Analysis Part I: Basic concepts and first analyses (2003) (nature.com)
In many cancer studies, the main outcome under assessment is the time to an event of interest.
Survival Analysis, Cancer Research, Statistics, Medical Research, Biostatistics
38 points by sebg 24 days ago | 9 comments
Stitches with electric charge found to speed up wound healing in rats (medicalxpress.com)
A team of chemical fiber and polymer material researchers in China has found that the use of internally produced, electrically charged sutures can speed up the healing process after surgery in rats.
Medical Research, Biomedical Engineering, Wound Healing
4 points by PaulHoule 26 days ago | 0 comments
Higher triglyceride glucose index linked to increased risk of cognitive decline (psypost.org)
A recent meta-analysis published in the Journal of Affective Disorders revealed that individuals with a higher triglyceride glucose (TyG) index face an increased risk of cognitive decline.
Health, Medical Research, Cognitive Decline, Meta-Analysis
8 points by XzetaU8 27 days ago | 0 comments
U.S. Study on Puberty Blockers Goes Unpublished Because of Politics, Doctor Says (nytimes.com)
An influential doctor and advocate of adolescent gender treatments said she had not published a long-awaited study of puberty-blocking drugs because of the charged American political environment.
Medical Research, Politics, Gender Identity, Health
45 points by 2OEH8eoCRo0 29 days ago | 41 comments
I got dysentery in a human challenge trial (eukaryotewritesblog.com)
This summer, I participated in a human challenge trial at the University of Maryland. I spent the days just prior to my 30th birthday sick with shigellosis.
Medical Research, Personal Experiences
49 points by yoyojojofosho 30 days ago | 50 comments
Chip-based tractor beam for biological particles (news.mit.edu)
MIT researchers have developed a miniature, chip-based “tractor beam,” like the one that captures the Millennium Falcon in the film “Star Wars,” that could someday help biologists and clinicians study DNA, classify cells, and investigate the mechanisms of disease.
Biotechnology, Physics, Medical Research
9 points by gmays 35 days ago | 0 comments
Commonly used arm positions can overestimate blood pressure readings: study (medicalxpress.com)
A study led by Johns Hopkins Medicine researchers concludes that commonly used ways of positioning the patient's arm during blood pressure (BP) screenings can substantially overestimate test results and may lead to a misdiagnosis of hypertension.
Medical Research, Health, Blood Pressure, Hypertension
331 points by wglb 38 days ago | 230 comments
Magnetically regulated gene therapy offers precise brain-circuit control (weill.cornell.edu)
A new technology enables the control of specific brain circuits non-invasively with magnetic fields, according to a preclinical study from researchers at Weill Cornell Medicine, The Rockefeller University and the Icahn School of Medicine at Mount Sinai.
Gene Therapy, Neuroscience, Medical Research, Biotechnology
13 points by geox 38 days ago | 2 comments
Covid-19 may increase the risk of heart attacks, strokes and deaths for 3 years (cnn.com)
Covid-19, Health, Medical Research, Public Health, Long-Term Effects
6 points by mhb 38 days ago | 0 comments
Valproate reopens critical-period learning of absolute pitch (2013) (nlm.nih.gov)
Music, Neuroscience, Learning, Medical Research
18 points by ChadNauseam 42 days ago | 6 comments
Could Microplastics Be a Driver for Early Onset Colorectal Cancer? (mdpi.com)
The incidence of colorectal cancer in those under 50 years of age (early onset colorectal cancer (EOCRC)) is increasing throughout the world.
Colorectal Cancer, Health, Medical Research, Microplastics
7 points by ClumsyPilot 46 days ago | 0 comments
World-first therapy using donor cells sends autoimmune diseases into remission (nature.com)
One woman and two men with severe autoimmune conditions have gone into remission after being treated with bioengineered and CRISPR-modified immune cells1.
Medical Research, Immunology, CRISPR, Autoimmune Diseases
147 points by Brajeshwar 47 days ago | 51 comments
Studies suggest a drug-free nasal spray could ward off respiratory infections (medicalxpress.com)
A new study details how a nasal spray formulated by investigators from Brigham and Women's Hospital may work to protect against viral and bacterial respiratory infections.
Medical Research, Nasal Spray, Respiratory Infections, Viruses, Bacteria
133 points by PaulHoule 47 days ago | 105 comments
Bacteria involved in gum disease linked to increased risk of head, neck cancer (medicalxpress.com)
More than a dozen bacterial species among the hundreds that live in people's mouths have been linked to a collective 50% increased chance of developing head and neck squamous cell carcinoma (HNSCC), a new study shows.
Medical Research, Cancer, Oral Health, Bacteria
72 points by wglb 54 days ago | 10 comments
Harvard medical student, ate 720 eggs in a month, cholesterol levels dropped (nypost.com)
This eggs-pert wasn’t yolk-ing around.
Health, Nutrition, Cholesterol, Diet, Medical Research
10 points by ivewonyoung 56 days ago | 2 comments
New defib placement more than doubles odds of surviving cardiac arrest (newatlas.com)
Placing defibrillator pads on the chest and back, rather than the usual method of putting two on the chest, increases the odds of surviving an out-of-hospital cardiac arrest by more than two-and-a-half times, according to a new study.
Medical Research, Health, Cardiac Arrest, Emergency Medicine
20 points by Brajeshwar 58 days ago | 3 comments
Giving T cells extra batteries supercharges them against cancer (newatlas.com)
T cells are our first line of defense against cancer, but the battle tends to exhaust them. Now, scientists have found a way to give them extra “batteries” to keep them fighting longer, with promising early results in mice.
Cancer, Biology, Immunology, Medical Research, Science
193 points by peutetre 58 days ago | 85 comments
Adderall in Higher Doses May Raise Psychosis Risk, Study Says (nytimes.com)
New research suggests that dosage plays a role in a rare side effect of A.D.H.D. stimulants.
Adderall, Mental Health, Health, Medical Research, Science
9 points by bookofjoe 66 days ago | 4 comments
Apple Hearing Study shares preliminary insights on tinnitus (apple.com)
The Apple Hearing Study is sharing new insights on tinnitus in one of the largest surveys to date.
Tinnitus, Health, Medical Research, Apple
258 points by mgh2 73 days ago | 161 comments
Gene Therapy Restores Vision (neurosciencenews.com)
After the treatment, one patient saw her first star. Another saw snowflakes for the first time. Other patients were newly able to navigate outside of the home or to read the labels on their child’s Halloween candy.
Gene Therapy, Medical Research, Vision, Biology
3 points by bookofjoe 75 days ago | 0 comments