Hacker News with Generative AI: Medical Research

Lowering bad cholesterol may cut risk of dementia by 26%, study suggests (theguardian.com)
Lowering your levels of bad cholesterol could reduce the risk of dementia by 26%, a study suggests.
New antibiotic that kills drug-resistant bacteria found in technician's garden (nature.com)
Researchers have discovered a new antibiotic molecule that targets a broad range of disease-causing bacteria — even strains resistant to commercial drugs — and is not toxic to human cells1.
First stroke rehabilitation drug discovered in mouse model (medicalxpress.com)
A new study by UCLA Health has discovered what researchers say is the first drug to fully reproduce the effects of physical stroke rehabilitation in model mice.
A breakthrough moment: Researchers discover new class of antibiotics (phys.org)
The last time a new class of antibiotics reached the market was nearly three decades ago—but that could soon change, thanks to a discovery by researchers at McMaster University.
Paralysed man stands again after receiving 'reprogrammed' stem cells (nature.com)
A paralysed man can stand on his own after receiving an injection of neural stem cells to treat his spinal cord injury.
High‑dose Vitamin D reduces disease activity in early multiple sclerosis onset (medicalxpress.com)
Researchers from CHU Nîmes, Université Montpellier, and multiple MS centers in France have found that oral cholecalciferol in doses of 100,000 IU every two weeks significantly reduced disease activity in clinically isolated syndrome and early relapsing‑remitting multiple sclerosis.
First-of-its-kind trial enables paralysed man to stand via stem cell injection (nature.com)
A paralysed man can stand on his own after receiving an injection of neural stem cells to treat his spinal cord injury.
Japanese scientists use stem cell treatment to restore movement in spinal injury (medicalxpress.com)
A stem cell treatment helped improve the motor function of two out of four patients with a spinal cord injury in the first clinical study of its kind, Japanese scientists said.
Parkinson's Gut Bacteria Link Suggests an Unexpected, Simple Treatment (sciencealert.com)
Researchers have suspected for some time that the link between our gut and brain plays a role in the development of Parkinson's disease.
Breakthrough stroke drug heals the brain to restore movement (newatlas.com)
There's newfound hope for stroke patients in recovery, with what researchers believe is the very first drug that can comprehensively deliver rehabilitation without the need for challenging long-term physical therapy.
Scientists Say NIH Officials Told Them to Scrub mRNA References on Grants (kffhealthnews.org)
National Institutes of Health officials have urged scientists to remove all references to mRNA vaccine technology from their grant applications, two researchers said, in a move that signaled the agency might abandon a promising field of medical research.
Parkinson's treatment closer as problematic protein imaged for first time (newatlas.com)
Scientists have finally pinned down a protein that’s largely responsible for Parkinson’s disease.
Giving blood frequently may make your blood cells healthier (newscientist.com)
Giving blood frequently may make your blood cells healthier
Stem cell therapy trial reverses "irreversible" damage to cornea (newatlas.com)
Eye injuries that damage the cornea are usually irreversible and cause blindness. But a new clinical trial has repaired this damage in patients thanks to a transplant of stem cells from their healthy eyes.
Engineered cartilage from nasal septum cells helps treat complex knee injuries (sciencedaily.com)
Injuries to the articular cartilage in different joints, including the knee, are painful and limit mobility. Therefore, researchers at the University of Basel and University Hospital Basel are developing cartilage implants using cells from the patient's nasal septum.
NIH.gov DNS servers down, making PubMed, BLAST, etc. unreachable [fixed] (nslookup.io)
Hemochromatosis patients can donate their blood rather than having it discarded (medicalxpress.com)
Thousands of people globally with an iron disorder have their blood regularly thrown out—Australian research shows it can be used to save lives
Verifiable science on modified PCR machine (github.com/ClemHeyd)
Scientific fraud kills. At Duke, 117 cancer patients received wrong treatments due to fabricated data. At Harvard, fake cardiac stem cell research led to years of invalid clinical trials. At Brigham and Women's, fictional pain studies changed treatment protocols nationwide.
Medical treatments devised for war can quickly be implemented in US hospitals (theconversation.com)
For decades, military doctors faced a critical challenge: What’s the best way to safely and effectively deliver oxygen to patients in remote combat zones, rural hospitals or disaster-stricken areas?
World-first experimental cancer treatment paves way for clinical trial (wehi.edu.au)
An experimental treatment for an aggressive and lethal brain cancer has today been published in Nature Medicine, paving the way for a clinical trial to be conducted by researchers at The Brain Cancer Centre.
President Trump's Cuts to Medical Research (nytimes.com)
The Trump administration stormed into office, loudly firing workers and closing diversity programs. But behind the scenes, it has also brought biomedical research to the brink of crisis by holding up much of the $47 billion the United States spends on the field every year.
Potential cellular 'master switch' capable of reversing senescence (studyfinds.org)
OSAKA, Japan — In the ongoing battle against aging, scientists have discovered a surprising new player that might hold the key to keeping cells young or making them old.
Pac-MANN diagnoses early-stage pancreatic cancer with 85% accuracy (newatlas.com)
Scientists at Oregon Health and Science University (OHSU) have developed a new blood test for pancreatic cancer, one of the most deadly forms of the disease.
Type 1 diabetes reversed by new cell transplantation technique (newatlas.com)
Transplanting insulin-producing cells along with engineered blood-vessel-forming cells has successfully reversed type 1 diabetes, according to a new preclinical study.
Decades of Research Misconduct Stalled an Alzheimer's Cure (sciencefriday.com)
In December 2021, I fell into one of the biggest and most disturbing stories of my career. A credible whistleblower with strong credentials in dementia research tipped me to a major case of apparent misconduct in his field. He produced convincing evidence that lab studies at the heart of the dominant hypothesis for the cause of Alzheimer’s disease might have been based on bogus data.
Immune markers of post COVID vaccination syndrome indicate future research (news.yale.edu)
AI cracks superbug problem in two days that took scientists years (bbc.co.uk)
A complex problem that took microbiologists a decade to get to the bottom of has been solved in just two days by a new artificial intelligence (AI) tool.
Migraine is more than a headache – a rethink offers hope (nature.com)
Migraine is more than a headache — a radical rethink offers hope to one billion people
How Medical Research Cuts Would Hit Colleges and Hospitals in Every State (nytimes.com)
A proposal by the Trump administration to reduce the size of grants for institutions conducting medical research would have far-reaching effects, and not just for elite universities and the coastal states where many are located.
First patient in UK tests new treatment for loss of sense of smell (theguardian.com)
Smell loss was a defining symptom of Covid, and for some people, a curse. Most people regain their sense of smell as their infection fades, but some never recover. It means not being able to tell if milk is off, if there’s a gas leak or what your newborn baby smells like.