Hacker News with Generative AI: Medical Research

Vitamin D Supplements Show Signs of Protection Against Biological Aging (massgeneralbrigham.org)
Results from the VITAL randomized controlled trial reveal that vitamin D supplementation helps maintain telomeres, protective caps at the ends of chromosomes that shorten during aging and are linked to the development of certain diseases.

Vitamins, Health, Aging, Science, Medical Research

12 points by gnabgib 36 days ago | 1 comments

Baby is healed with first personalized gene-editing treatment (nytimes.com)
The technique used on a 9½-month-old boy with a rare condition has the potential to help people with thousands of other uncommon genetic diseases.

Gene Editing, Medical Research, Genetic Diseases, Personalized Medicine

1257 points by jbredeche 43 days ago | 531 comments

Analgesic effects of non-surgical&non-interventional treatment for low back pain (ebm.bmj.com)
A total of 301 trials (377 comparisons) provided data on 56 different treatments or treatment combinations.

Pain Management, Medical Research, Back Pain, Treatment

3 points by bookofjoe 43 days ago | 0 comments

'Inverse vaccines': promise of a 'holy grail' treatment for autoimmune diseases (theguardian.com)
Autoimmune diseases affect as many as 800 million people around the world – around one in 10 of us. From multiple sclerosis and lupus to type one diabetes and rheumatoid arthritis, these conditions all share a common trait: the body’s own immune system turns against itself.

Autoimmune Diseases, Medical Research, Healthcare, Immunology

5 points by pseudolus 47 days ago | 0 comments

Covid-19 vaccines associated with a reduction in ovarian reserve in rats (nlm.nih.gov)
This study aimed to elucidate the effects of messenger RNA (mRNA) and inactivated coronavirus disease 2019 (COVID-19) vaccines on ovarian histology and reserve in rats.

COVID-19, Vaccines, Science, Medical Research, Animal Studies

7 points by b800h 47 days ago | 5 comments

'A very exciting day': Canadian design may revolutionize the way ALS is treated (ctvnews.ca)
‘A very exciting day’: Canadian design may revolutionize the way ALS is treated

Medical Research, ALS, Canada, Innovation

9 points by amichail 49 days ago | 0 comments

PTSD Patients Show Long-Term Benefits with Vagus Nerve Stimulation (news.utdallas.edu)
In a first-of-its-kind clinical study, scientists at The University of Texas at Dallas and Baylor University Medical Center showed that patients with treatment-resistant PTSD were symptom-free up to six months after completing traditional therapy paired with vagus nerve stimulation (VNS).

PTSD, Medical Research, Neuroscience, Treatment

3 points by geox 49 days ago | 0 comments

Once-Weekly Semaglutide in Adults with Alcohol Use Disorder: A RCT (jamanetwork.com)
In this randomized clinical trial, relative to placebo, low-dose semaglutide reduced the amount of alcohol consumed during a posttreatment laboratory self-administration procedure.

Pharmacology, Health, Medical Research

4 points by Anon84 50 days ago | 0 comments

New Brunswick has no mystery neurological disease, scientific study concludes (cbc.ca)
A new scientific study has found no evidence of a mystery brain disease in New Brunswick, says a report published Wednesday in the Journal of the American Medical Association, known as JAMA.

Medical Research, Neurology, New Brunswick, Canada

5 points by cpncrunch 51 days ago | 0 comments

Vagus Nerve Stimulation Erases PTSD: Study (neurosciencenews.com)
In a first-of-its-kind clinical study, scientists at The University of Texas at Dallas and Baylor University Medical Center showed that patients with treatment-resistant PTSD were symptom-free up to six months after completing traditional therapy paired with vagus nerve stimulation (VNS).

PTSD, Neuroscience, Medical Research, Treatment

137 points by rmason 51 days ago | 78 comments

Effects of lifestyle changes on cognitive impairment due to Alzheimer's (2024) (biomedcentral.com)
We report the first randomized, controlled trial showing that an intensive multimodal lifestyle intervention may significantly improve cognition and function and may allay biological features in many patients with MCI or early dementia due to AD after 20 weeks.

Alzheimer's, Cognitive Impairment, Lifestyle Changes, Medical Research, Clinical Trials

11 points by chillpenguin 52 days ago | 3 comments

Ovarian Tissue Freezing Could Prevent Menopause–Possibly Forever (2024) (medicine.yale.edu)
Most women agree that menopause has its advantages and disadvantages. Some relish the end of menstruation and concerns about unplanned pregnancies, while others dread the possibililty of hot flashes, moodiness, and other unpleasant symptoms. What some women consider a brief and barely noticeable phase in their lives can evolve into lasting changes and discomfort for others.

Medical Research, Menopause, Reproduction

6 points by tempestn 53 days ago | 0 comments

Effects of repetitive transcranial magnetic stimulation on sleep bruxism (nlm.nih.gov)
The purpose of this study was to investigate the effects of repetitive transcranial magnetic stimulation (rTMS) on patients with sleep bruxism (SB).

Medical Research, Neurology, Sleep Disorders

53 points by amelius 54 days ago | 5 comments

Origins of common lung cancer that affects smokers discovered (medicalxpress.com)
The "cell of origin" of the second most common lung cancer and the way that it becomes dominant in the lung have been discovered in a new study in mice and humans by researchers at UCL, the Wellcome Sanger Institute and the University of Cambridge.

Lung Cancer, Science, Medical Research, Genetics

12 points by mdp2021 57 days ago | 0 comments

Medicine Spares Cancer Patients from Grisly Surgeries and Harsh Therapies (nytimes.com)
For a limited group of cancer patients who have solid tumors in the stomach, rectum, esophagus and other organs, an immunotherapy trial offered stunning results.

Cancer Treatment, Immunotherapy, Medicine, Medical Research

8 points by bookofjoe 58 days ago | 1 comments

In kids, EEG monitoring of consciousness safely reduces anesthetic use (news.mit.edu)
Newly published results of a randomized, controlled clinical trial in Japan among more than 170 children aged 1 to 6 who underwent surgery show that by using electroencephalogram (EEG) readings of brain waves to monitor unconsciousness, an anesthesiologist can significantly reduce the amount of the anesthesia administered to safely induce and sustain each patient’s anesthetized state.

Medical Research, Anesthesia, Children's Health, Brain Science

139 points by LorenDB 58 days ago | 85 comments

My fight to unlock cannabis and psychedelic drugs for use in medical research (nature.com)
From the earliest days of her career, physician Sue Sisley has been passionate about caring for US military veterans.

Medical Research, Cannabis, Psychedelic Drugs, Veterans

10 points by bookofjoe 59 days ago | 0 comments

Methylene Blue Address Vascular-Hypometabolism in Alzheimer's Disease (gethealthspan.com)
Alzheimer’s disease (AD) is often associated with amyloid plaques and neurofibrillary tangles, yet growing evidence supports a vascular-hypometabolism hypothesis in which cerebral hypoperfusion and mitochondrial dysfunction—particularly at the level of cytochrome c oxidase—drive early disease processes.

Alzheimer's Disease, Neuroscience, Medical Research, Health

5 points by dtawfik1 62 days ago | 0 comments

Sham Surgery (wikipedia.org)
Sham surgery (or placebo surgery) is a faked surgical intervention that omits the step thought to be therapeutically necessary.

Medicine, Placebo Effect, Medical Research

5 points by airstrike 63 days ago | 0 comments

Strong humming for one hour daily to terminate chronic rhinosinusitis (2006) (nlm.nih.gov)
Strong humming for one hour daily to terminate chronic rhinosinusitis in four days: a case report and hypothesis for action by stimulation of endogenous nasal nitric oxide production

Health, Medical Research, Alternative Medicine, Case Studies

15 points by bfoks 63 days ago | 0 comments

Cluster headaches are 'the most painful condition on the planet' (theguardian.com)
The condition is more excruciating than childbirth or gunshot wounds, but little understood. An online community of ‘clusterheads’ are self-experimenting with psilocybin – with promising results

Health, Pain, Psilocybin, Medical Research, Online Communities

10 points by pseudolus 65 days ago | 0 comments

Clinical trial: novel nutritional formula treats gut microbial overgrowth (medicalxpress.com)
Cedars-Sinai researchers have developed a novel nutritional formula, mBiota Elemental, a palatable elemental diet (PED) that reduces the abundance of key gut microbiome taxa and improves symptoms in patients with small intestinal bacterial overgrowth (SIBO) and intestinal methanogen overgrowth (IMO).

Clinical Trials, Gut Health, Nutrition, Medical Research

66 points by wglb 65 days ago | 25 comments

Study Reveals an Amount of Plastic in the Arteries of Stroke Patients (businessinsider.com)
Tiny, microscopic bits of plastic have been found almost everywhere researchers look — including throughout the human body.

Health, Medical Research, Plastic Pollution, Stroke

6 points by gpi 65 days ago | 1 comments

Marijuana hospital visits linked to dementia diagnosis within 5 years – a study (cnn.com)

Marijuana, Dementia, Health, Studies, Medical Research

44 points by avodonosov 67 days ago | 96 comments

Cigarette smoking: an underused tool in high-performance endurance training (nlm.nih.gov)
The review paper is a staple of medical literature and, when well executed by an expert in the field, can provide a summary of literature that generates useful recommendations and new conceptualizations of a topic. However, if research results are selectively chosen, a review has the potential to create a convincing argument for a faulty hypothesis. Improper correlation or extrapolation of data can result in dangerously flawed conclusions.

Health, Science, Medical Research, Endurance Training

25 points by erhmmmm 67 days ago | 8 comments

A unique sound alleviates motion sickness (nagoya-u.ac.jp)
A research group led by Takumi Kagawa and Masashi Kato at Nagoya University Graduate School of Medicine has discovered that using “a unique sound stimulation technology”—a device that stimulates the inner ear with a specific wavelength of sound—reduces motion sickness.

Motion Sickness, Sound, Technology, Medical Research

212 points by miles 69 days ago | 95 comments

Popular CT Scans Could Account for 5% of All Cancer Cases a Year (ucsf.edu)
Computed tomography (CT) scans may account for 5% of all cancers annually, according to a new study out of UC San Francisco that cautions against overusing and overdosing CTs.

Cancer, Health, Medical Technology, Medical Research

26 points by hsuduebc2 69 days ago | 9 comments

Differentiation of human dental pulp stem cells into neuron-like cells (biomedcentral.com)
Human dental pulp stem cells (hDPSCs) constitute a promising alternative for central nervous system (CNS) cell therapy.

Stem Cells, Biology, Neuroscience, Medical Research

7 points by PaulHoule 70 days ago | 0 comments

Phase I/II trial of iPS-cell-derived dopaminergic cells for Parkinson's disease (nature.com)
Parkinson’s disease is caused by the loss of dopamine neurons, causing motor symptoms.

Medical Research, Parkinson's Disease, Clinical Trials

28 points by LinuxBender 71 days ago | 0 comments

New strategy may enable cancer monitoring from blood tests alone (medicalxpress.com)
A new, error-corrected method for detecting cancer from blood samples is much more sensitive and accurate than prior methods and may be useful for monitoring disease status in patients following treatment, according to a study by Weill Cornell Medicine and New York Genome Center investigators.

Cancer, Healthcare, Medical Research, Blood Tests

7 points by wglb 71 days ago | 1 comments