Hacker News with Generative AI: Immunotherapy

Pancreatic cancer: blocked nerves as a possible new treatment strategy (dkfz.de)
Pancreatic cancer is fueled by connections to the nervous system. This is reported by scientists from the German Cancer Research Center (DKFZ) and the Heidelberg Institute for Stem Cell Technology and Experimental Medicine (HI-STEM)* in their current publication in Nature. The team discovered that the tumor reprograms the neurons for its own benefit. In mice, blocking nerve function inhibited cancer growth and increased the sensitivity of tumor cells to certain chemotherapies and immunotherapies.

Cancer Research, Neuroscience, Treatment, Immunotherapy, Mice Studies

4 points by gmays 3 days ago | 0 comments

Immunotherapy Extended President Jimmy Carter's Life (cancerresearch.org)
Jimmy Carter, the 39th president of the United States, passed away on December 29, 2024, at the age of 100 in his hometown of Plains, Georgia. The former U.S. president had been in hospice care since February 2023 following declining health.

Immunotherapy, Cancer, Health, Politics

23 points by wwarner 25 days ago | 4 comments

Promising early data in triple negative breast cancer (statnews.com)
New data suggests researchers may have found one of their most promising candidates yet for the next generation in immunotherapy drugs — bispecific antibodies targeting two key proteins in cancer, PD1 or PD-L1 and VEGF.A small early trial on one such bispecific compound was presented by researchers working with BioNTech at the San Antonio Breast Cancer Symposium on Tuesday. The bispecific compound, called BNT-327, had positive results in patients with triple negative breast cancer.

Cancer, Immunotherapy, Drugs, Clinical Trials

10 points by doener 73 days ago | 1 comments

mRNA cancer vaccine shows potential for advanced stage cancer patients (kcl.ac.uk)
Interim data from the Phase I dose escalation part of the mRNA cancer immunotherapy (mRNA-4359), show promise in patients with advanced solid cancers.

Cancer, Vaccines, Clinical Trials, Immunotherapy

13 points by nopakos 158 days ago | 0 comments

Immunotherapy Is Changing Cancer Treatment Forever (nymag.com)

Cancer Treatment, Immunotherapy, Medicine

331 points by bookofjoe 222 days ago | 154 comments

New mRNA cancer vaccine triggers fierce immune response to fight brain tumor (medicalxpress.com)