Hacker News with Generative AI: Pharmacology

First stroke rehabilitation drug discovered in mouse model (medicalxpress.com)
A new study by UCLA Health has discovered what researchers say is the first drug to fully reproduce the effects of physical stroke rehabilitation in model mice.
Metformin-regulated glucose flux from the circulation to the intestinal lumen (nature.com)
Through a retrospective analysis of existing FDG PET-MRI images, we recently demonstrated that metformin increases the accumulation of FDG in the intestinal lumen, suggesting that metformin stimulates glucose excretion into the intestine. However, the details of this phenomenon remain unclear. We here investigate the detailed dynamics of intestinal glucose excretion, including the rate of excretion and the metabolism of excreted glucose, in both the presence and absence of metformin.
Antibiotics,vaccinations, anti-inflammatory meds linked to reduced dementia risk (medicalxpress.com)
Antibiotics, antivirals, vaccinations and anti-inflammatory medication are associated with reduced risk of dementia, according to new research that looked at health data from over 130 million individuals.
The Compounding Loophole (astralcodexten.com)
Now that we’ve gone over the pharmacology of the GLP-1 agonists, let’s get back to the economics.
Resiniferatoxin (wikipedia.org)
WTH Is Cerebrolysin, Actually? (moreisdifferent.blog)
Cathinone and Psilocybin in Cicada Pathogens (2019) (sciencedirect.com)
CB1 Receptor Negative Allosteric Modulators to Reverse Cannabinoid Toxicity (mdpi.com)
MDMA enhances empathy-like behaviors in mice via 5-HT release (science.org)