Hacker News with Generative AI: Animal Studies

Model Organisms Are Not Static (asimov.press)
About 70 percent of scientists say they have tried and failed to reproduce an experiment performed by their peers. And animal studies are, perhaps, among the least reproducible of all experiments because, in an effort to reduce the number of animals used in research, scientists often avoid repeating them to confirm positive results.1 When animal studies are replicated, however, they often yield different outcomes.

Science, Biology, Research, Reproducibility, Animal Studies

44 points by mailyk 8 days ago | 14 comments

Mice grow bigger brains when given this stretch of human DNA (nature.com)
Researchers have identified a genetic dial in the human brain that, when inserted in mice, boosts their brain size by about 6.5%.

Genetics, Neuroscience, Research, Animal Studies

62 points by pavel_lishin 9 days ago | 44 comments

Covid-19 vaccines associated with a reduction in ovarian reserve in rats (nlm.nih.gov)
This study aimed to elucidate the effects of messenger RNA (mRNA) and inactivated coronavirus disease 2019 (COVID-19) vaccines on ovarian histology and reserve in rats.

COVID-19, Vaccines, Science, Medical Research, Animal Studies

7 points by b800h 12 days ago | 5 comments

Beef fat prevents alcoholic liver disease in the rat (nlm.nih.gov)
The amount and type of dietary fat is thought to be important in the pathogenesis of alcoholic liver disease (ALD).

Science, Health, Nutrition, Liver Disease, Animal Studies

7 points by typeofhuman 169 days ago | 4 comments

Beef fat prevents alcoholic liver disease in the rat (nlm.nih.gov)
The amount and type of dietary fat is thought to be important in the pathogenesis of alcoholic liver disease (ALD).

Health, Science, Nutrition, Animal Studies

6 points by NavinF 215 days ago | 2 comments

Eating less can lead to a longer life: study in mice shows why (nature.com)
Cutting calorie intake can lead to a leaner body — and a longer life, an effect often chalked up to the weight loss and metabolic changes caused by consuming less food.

Health, Longevity, Diet, Animal Studies, Science

8 points by pseudolus 226 days ago | 0 comments

Gut Microbiome Disruption Linked to Aggression (neurosciencenews.com)
A new study led by Prof. Omry Koren and graduate student Atara Uzan-Yuzari from the Azrieli Faculty of Medicine at Bar-Ilan University has unveiled significant evidence connecting the gut microbiome to aggressive behavior in mice.

Gut Microbiome, Aggression, Neuroscience, Animal Studies

5 points by NalNezumi 241 days ago | 0 comments

Omega-3 intake counteracts symptoms of anxiety and depression in mice (psypost.org)
A study on mice found that adding omega-3 polyunsaturated fatty acids to their diets effectively counteracts depressive and anxiety-like behaviors induced by stress.

Science, Mental Health, Nutrition, Animal Studies

293 points by geox 244 days ago | 158 comments

Switching off inflammatory protein leads to longer, healthier lifespans in mice (sciencedaily.com)

Biotechnology, Aging, Animal Studies, Health

6 points by willvk 308 days ago | 0 comments

Mouse Heaven or Mouse Hell? (2022) (sciencehistory.org)

Animal Studies, Science, History

69 points by ajuhasz 319 days ago | 57 comments

High-fat diet, microbiome-gut-brain axis signaling, and anxiety in rats (biomedcentral.com)

Diet, Neuroscience, Animal Studies, Gut Microbiome

20 points by gnabgib 331 days ago | 0 comments

Five years later, naked mole-rat mortality rates still defy Gompertzian laws (springer.com)

Biology, Longevity, Animal Studies

10 points by beefman 332 days ago | 0 comments

Exercise rewires the brain, helping mice forget traumatic and addictive memories (kyushu-u.ac.jp)