Hacker News with Generative AI: Immunology

Woman who had pioneering cancer treatment 18 years ago still in remission (theguardian.com)
A woman treated with a pioneering type of immunotherapy for a solid tumour has been in remission for more than 18 years with no further treatments, experts have revealed.

Cancer Treatment, Medical Breakthrough, Immunology, Health, Science

129 points by ranit 4 days ago | 31 comments

Mitochondrial swap from cancer to immune cells thwarts anti-tumour defences (nature.com)
Immune cells can destroy cancer, but tumours often evade such responses. The bidirectional transfer of mitochondria between cancer and immune cells is a newly discovered mechanism that thwarts anticancer defences.

Cancer, Biology, Immunology, Science

5 points by gronky_ 25 days ago | 0 comments

Scientists Say They've Discovered How Cancer Hijacks and Corrupts Immune Cells (singularityhub.com)
Cancer cells steal from and poison the cells tasked with fighting them off.

Cancer, Immunology, Biology, Science

5 points by Brajeshwar 28 days ago | 0 comments

Micro nutrients as immunomodulators in the ageing population (biomedcentral.com)
Immunosenescence, the slow degradation of immune function over time that is a hallmark and driver of aging, makes older people much more likely to be killed by common infections (such as flu) than young adults, but it also contributes greatly to rates of chronic inflammation in later life.

Immunology, Aging, Health, Biomedicine

4 points by haltingproblem 51 days ago | 0 comments

Novel link between cell nutrition and identity could improve immunotherapies (genengnews.com)
The immune system relies on specialized “effector” T cells to fight off pathogens. However, in chronic infections such as cancer or HIV, the perpetual activation of these cells can turn them into “exhausted” T cells unable to continue fighting.

Immunology, Cancer, Medicine, T cells, Gene Editing

31 points by gnabgib 71 days ago | 2 comments

Designer cells 'reboot' immune system in 3 different autoimmune diseases (livescience.com)

Biotechnology, Medicine, Immunology, Autoimmune Diseases

5 points by geox 94 days ago | 0 comments

Viral trapdoor: Scientists discover how a protein protects against HIV, herpes (medicalxpress.com)
A group of researchers discovered how a protein linked to the human immune system wards off HIV-1 and herpes simplex virus-1 by assembling structures in the cell that lure in these viruses and then trap them or even take them apart.

HIV, Herpes, Immunology, Viral Research, Science

6 points by PaulHoule 116 days ago | 1 comments

World-first therapy using donor cells sends autoimmune diseases into remission (nature.com)
One woman and two men with severe autoimmune conditions have gone into remission after being treated with bioengineered and CRISPR-modified immune cells1.

Medical Research, Immunology, CRISPR, Autoimmune Diseases

147 points by Brajeshwar 139 days ago | 51 comments

SARS-CoV-2-specific plasma cells not durably in bone marrow after mRNA vaccine (nature.com)
As of August 2024, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected over 776 million people worldwide and killed 7.1 million, including 1.2 million in the United States alone1.

COVID-19, Vaccines, Immunology, Science, Medicine

9 points by cempaka 143 days ago | 2 comments

Giving T cells extra batteries supercharges them against cancer (newatlas.com)
T cells are our first line of defense against cancer, but the battle tends to exhaust them. Now, scientists have found a way to give them extra “batteries” to keep them fighting longer, with promising early results in mice.

Cancer, Biology, Immunology, Medical Research, Science

193 points by peutetre 150 days ago | 85 comments

First mouse model with complete, functional human immune system (news.uthscsa.edu)

Medicine, Biology, Immunology, Genetics

7 points by geox 230 days ago | 0 comments

Tissue T cell activation and viral RNA Persist 2 Years after SARS-CoV-2 (science.org)

COVID-19, Immunology, Science, Health, Research

6 points by thenerdhead 231 days ago | 0 comments

Light targets cells for death and triggers immune response with laser precision (news.illinois.edu)

Medical Technology, Cancer Treatment, Immunology, Laser Technology

24 points by geox 235 days ago | 2 comments

Discovery of new white blood cell function (cam.ac.uk)