Hacker News with Generative AI: CRISPR

Two Nobel Prize winners want to cancel their own CRISPR patents in Europe (technologyreview.com)
In the decade-long fight to control CRISPR, the super-tool for modifying DNA, it’s been common for lawyers to try to overturn patents held by competitors by pointing out errors or inconsistencies.

CRISPR, Patents, Science, Biotechnology, Law

167 points by thisismytest 4 days ago | 120 comments

New CRISPR system for gene silencing doesn't rely on cutting DNA (phys.org)
Scientists from Vilnius University's (VU) Life Sciences Center (LSC) have discovered a unique way for cells to silence specific genes without cutting DNA.

Biotechnology, Genetics, CRISPR, Gene Editing, Science

4 points by cjnicholls 8 days ago | 0 comments

Swiss researchers find unwanted CRISPR side effects (swissinfo.ch)
Under certain circumstances, the targeted correction of faulty sections in the genome can trigger new genetic defects.

Genetics, Science, CRISPR, Health, Research

7 points by belter 12 days ago | 1 comments

Genetic repair via CRISPR can inadvertently introduce other defects (phys.org)
The CRISPR molecular scissors have the potential to revolutionize the treatment of genetic diseases. This is because they can be used to correct specific defective sections of the genome. Unfortunately, however, there is a catch: under certain conditions, the repair can lead to new genetic defects—as in the case of chronic granulomatous disease.

Genetics, CRISPR, Medical Research

111 points by amichail 13 days ago | 65 comments

Jennifer Doudna on the Brave New World Being Ushered in by Gene Editing (newyorker.com)
In 2012, the biochemist Jennifer Doudna and her colleague Emmanuelle Charpentier developed a method for using RNA-guided proteins to edit specific sections of DNA.

Gene Editing, Biology, Science, CRISPR, Bioethics

6 points by mitchbob 32 days ago | 1 comments

World-first therapy using donor cells sends autoimmune diseases into remission (nature.com)
One woman and two men with severe autoimmune conditions have gone into remission after being treated with bioengineered and CRISPR-modified immune cells1.

Medical Research, Immunology, CRISPR, Autoimmune Diseases

147 points by Brajeshwar 47 days ago | 51 comments

Bridge RNAs direct programmable recombination of target and donor DNA (nature.com)

Genetics, Molecular Biology, CRISPR, Bioengineering, Scientific Research

10 points by breck 147 days ago | 1 comments

CRISPR-GPT: An LLM Agent for Automated Design of Gene-Editing Experiments (biorxiv.org)