Hacker News with Generative AI: Weight Loss

Intermittent fasting is effective for weight loss and improves cardio health (sciencedaily.com)
A team of scientists led by the University of Granada (UGR), the Public University of Navarra (UPNA) and the CIBER has shown that intermittent fasting (reducing the number of hours of intake and extending the hours of fasting each day) is an effective method for losing weight and improves cardiovascular health in people with obesity problems.
The benefits of Ozempic and its kin may extend far beyond weight loss (sciencenews.org)
This year, the popularity of the diabetes and weight-loss drug semaglutide has continued to surge. You’ve probably seen ads on social media or heard from friends who’ve tried top-selling brand-name versions, Ozempic and the higher-dose variety Wegovy (SN: 6/29/24, p. 5), or read accounts of people microdosing these drugs.
Weight loss drugs may also treat addiction, Alzheimer's, and heart disease (arstechnica.com)
Pharmaceutical companies are already cashing in on their other health benefits.
Fat Cells Remember Obesity, Driving the Yo-Yo Effect (technologynetworks.com)
Researchers uncover how epigenetic memory in fat cells drives the yo-yo effect, making weight regain more likely.
Fat cells have a memory of obesity – hinting at why it's hard to keep weight off (nature.com)
Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity, research1 shows — a finding that might help to explain why it can be hard to stay trim after a weight-loss programme.
Weight-loss drug found to shrink muscle in mice, human cells (ualberta.ca)
Trendy weight-loss drugs making headlines for shrinking waistlines may also be shrinking the human heart and other muscles, according to a new University of Alberta study whose authors say should serve as a “cautionary tale” about possible long-term health effects of these drugs.
Ozempic Could Prevent Diabetes. Should It Be Used for That? (nytimes.com)
New research shows that weight loss medications can stop the progression of prediabetes. Experts don’t all agree on such a use for the drugs.
As Ozempic turns consumers off processed foods, junk food industry fights back (nytimes.com)
As revolutionary new weight-loss drugs turn consumers off ultraprocessed foods, the industry is on the hunt for new products.
Fat cells have 'memory' of obesity – hinting at why it's hard to keep weight off (nature.com)
Even after drastic weight loss, the body’s fat cells carry the ‘memory’ of obesity, research1 shows — a finding that might help to explain why it can be hard to stay trim after a weight-loss programme.
A new stronger Ozempic is coming. Here's what to know (qz.com)
Novo Nordisk (NVO-4.34%) teased some new details about a potential Ozempic successor during a call with investors Tuesday.
Weight-loss surgery down 25 percent as anti-obesity drug use soars (news.harvard.edu)
A new study examining a large sample of privately insured patients with obesity found that use of drugs such as Ozempic and Wegovy as anti-obesity medications more than doubled from 2022 to 2023.
Exercise Paradox (wikipedia.org)
The exercise paradox,[1] also known as the workout paradox,[2] refers to the finding that physical activity, while essential for maintaining overall health, does not necessarily lead to significant weight loss or increased calorie expenditure.[3] This paradox challenges the common belief that more exercise equates to more calories burned and consequently, more weight loss.[4]
New study finds obesity operations dropped 25.6% in 2023 due to GLP-1 drugs (statnews.com)
For people with obesity, surgeries that shrink, reshape, or otherwise alter the anatomy of the stomach have long reigned supreme as the surest way to weight loss. But in the last few years, with the approval of GLP-1 drugs like Wegovy and Zepbound, more and more people are opting for obesity medicines over gold-standard surgical treatments.
'Miracle' weight-loss drugs could lead to debilitating brittle bones, fractures (dailymail.co.uk)
Experts warn that 'miracle' weight-loss drugs could lead to fractures and brittle bones.
Predicting Weight Loss with Machine Learning (feelingbuggy.com)
I've been writing on my blog about following a ketogenic diet to manage my mental illness - see Finding Hope After Decades of Struggle. One of the major wins I've been able to achieve so far is losing over 20 kg in the last couple of months.
India's copycat drugmakers gear up to offer cheaper weight-loss drugs (ft.com)
India’s copycat drugmakers gear up to offer cheaper weight-loss drugs
Modern MBA: The Dirty Business of Weight Loss [video] (youtube.com)
GLP-1 pills are coming, and they could revolutionize weight-loss treatment (cnn.com)
GLP-1 agonists (Wegovy, Ozempic,) cause disproportionate muscle loss (ft.com)
Endurance exercise without weight loss may reduce body fat (medicalxpress.com)
Participating in a high volume of exercise over a short period of time, such as cycling hundreds of miles in a few days, could reduce body fat levels without weight loss.
Roche data shows stomach-churning side effects of weight-loss drugs (ft.com)
Roche data shows stomach-churning side effects of weight-loss drugs
Biology's a B*Tch: Reasons It's So Hard to Keep Weight Off (npr.org)
Weight-loss jabs could 'slow down the clock' on biological ageing (thetimes.com)
Weight-loss jabs could ‘slow down the clock’ on biological ageing
My guess why potatoes creates weight loss (metrep.substack.com)
Eli Lilly's weight loss drug slashes the risk of diabetes in long-term trial (cnbc.com)
Eli Lilly's weight loss drug slashes the risk of developing diabetes by 94% (cnbc.com)
Lilly says weight loss drug cuts heart failure risk by 38% in trial (reuters.com)
Weight-loss drugs are causing people to spend less at the grocery store: study (nypost.com)
The New Holy Grail for Weight-Loss Drugs Is Sleep Apnea (wsj.com)
Not Everyone Loses Weight on Ozempic (wired.com)