Epigenetic inheritance of diet-induced and sperm-borne mitochondrial RNAs
(nature.com)
Apart from Mendelian inheritance, fathers use alternative routes for intergenerational information transfer. One of these is a complex, dynamic and environment-sensitive pool of sncRNAs that are stored in mature spermatozoa1, delivered to the oocytes at fertilization9, and influence embryonic development10,11 and adult phenotypes1,2,3,4,5,6,7,11.
Apart from Mendelian inheritance, fathers use alternative routes for intergenerational information transfer. One of these is a complex, dynamic and environment-sensitive pool of sncRNAs that are stored in mature spermatozoa1, delivered to the oocytes at fertilization9, and influence embryonic development10,11 and adult phenotypes1,2,3,4,5,6,7,11.